![APHIDICOLIN,CAS [38966-21-1], confocal immunofluorescent analysis of HeLa cells, untreated (left) or synchronized at the G1/S border by aphidicolin treatment (right), using FoxM1 (D12D5) XP Rabbit mAb (green). Actin filaments were labeled with DY-554 phal](http://www.agscientific.com/media/catalog/product/cache/1/thumbnail/56x/5e06319eda06f020e43594a9c230972d/f/i/file_2_5.jpg "APHIDICOLIN,CAS [38966-21-1], confocal immunofluorescent analysis of HeLa cells, untreated (left) or synchronized at the G1/S border by aphidicolin treatment (right), using FoxM1 (D12D5) XP Rabbit mAb (green). Actin filaments were labeled with DY-554 phal")
![APHIDICOLIN,CAS [38966-21-1], In response to ionizing radiation or other agents that generate DSBs, many DNA repair factor such as p53-binding protein 1 (53BP1) of the breast cancer susceptibility 1 (BRCA1) tumor suppressor rapidly localize to sites near](http://www.agscientific.com/media/catalog/product/cache/1/thumbnail/56x/5e06319eda06f020e43594a9c230972d/f/i/file_2_6.jpg "APHIDICOLIN,CAS [38966-21-1], In response to ionizing radiation or other agents that generate DSBs, many DNA repair factor such as p53-binding protein 1 (53BP1) of the breast cancer susceptibility 1 (BRCA1) tumor suppressor rapidly localize to sites near")
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Product Description
Aphidicolin is a reversible Inhibitor of eukaryotic nuclear DNA replication. Aphidicolin blocks cell cycle at early S-phase.
Attached is a published reference from researchers who have used our Aphidicolin product. We respectfully thank them for their trust in our product. Inquire for a full reference list.
http://www.jbc.org/content/280/48/39752.full.pdf+html
Additional Information
COA Documentation: |
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| Product Number | A-1026 |
| CAS # | CAS [38966-21-1] |
| Chemical Name | (3-α,4-α,5-α,17-α)-3,17-Dihydroxy-4-methyl-9,15-cyclo-C,18-dinor-14,15-secoandrostane-4,17-dimethanol |
| Chemical Formula | C20H34O4 |
| Appearance | Off-White Powder |
| Melting Point | MP: 218-220°C |
| Merck Index | Merck Index: 13.734.2001 |
| Molecular Weight | M.W. 338.5 |
| Purity | Purity: >98% |
| Solubility | Soluble in Methanol, DMSO and Ethanol |
| Storage Temp | +4°C |
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