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Calcium Signaling

Calcium is a common signaling mechanism, as once it enters the cytoplasm it exerts allosteric regulatory affects on many enzymes and proteins.  Our most popular Calcium signaling reagents are:

Calcimycin  also known as (A23187)  is a calcium ionophore with antibiotic properties that kill gram positive bacteria and fungi. This ionophore increases intracellular Ca2+ concentrations, and can either initiate or prevent apoptosis in different cell types A23187.

Ionomycin is selective for calcium ions (Ca2+); it increases membrane permeability to calcium. Reported to be more effective Ca++ ionophore than A23187.

Calmodulins(CaM) is a ubiquitous, calcium-binding protein that can bind to and regulate a multitude of different protein targets, thereby affecting many different cellular functions.

A.G. Scientific delivers quality assured reagents directly to scientists, from small-scale to bulk orders. Our leadership in bulk supply allows us to provide custom product packaging and create multiple product forms. We offer “just in time” delivery, private labeling, and custom formulations for specific research needs.

 

 

 

 

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(-)-Arctigenin, Arctium lappa
Product Number: A-1308

Product Name Price Qty
(-)-Arctigenin, Arctium lappa - 1x25 mg
$70.00
Lignan derivative, which shows anti-tumor, anti-inflammatory, immunomodulatory and neuroprotective activities. Down-regulates anti-apoptotic Learn More

(-)-Arctiin, Arctium lappa
Product Number: A-1306

Product Name Price Qty
(-)-Arctiin, Arctium lappa - 1x25 mg
$60.00
Lignan derivative with anti-tumor activities. Down-regulates anti-apoptotic protein Bcl-XL. Potent inhibitor of HIV Type-I Integrase and DNA Learn More

(S)-Roscovitine
Product Number: R-2022

Product Name Price Qty
(S)-Roscovitine - 1x1 mg
$40.00
the (S)-enantiomer of the potent cyclin-dependent kinase (cdk) inhibitor Roscovitine (#R1016). Potently inhibits p34cdc2/cyclin B kinase (IC Learn More

(±)-BAY-K-8644
Product Number: B-1019

Product Name Price Qty
(±)-BAY-K-8644 - 1x5 mg
$165.00
A Ca2+ slow channel agonist. Learn More

1-D-3-Deoxy-phophatidylinositol
Product Number: D-1113

Product Name Price Qty
1-D-3-Deoxy-phophatidylinositol - 1x100 μg
$30.00
1-D-3-Deoxy-phophatidylinositol - 1x1 mg
$150.00
Antimetabolite of phosphatidylinositol-3-phosphate. An inhibitor of cancer cell colony formation. Learn More

3-F-Deoxy-Ins(1,4,5)P3. 6Na
Product Number: D-1109

Product Name Price Qty
3-F-Deoxy-Ins(1,4,5)P3. 6Na - 1x100 ug
$40.00
Equal to Ins(1,4,5)P3 in releasing intracellular calcium. The 3-position is blocked by fluorine so it can not be converted to Ins(1,3,4,5)P4 Learn More

3-O-Acetyl-11-keto-beta-boswellic acid, Boswellia serrata
Product Number: B-1265

Product Name Price Qty
3-O-Acetyl-11-keto-beta-boswellic acid, Boswellia serrata - 1x5 mg
$130.00
Boswellic acid derivative, which shows anti-tumor and anti-inflammatory activities. Potent non-redox, noncompetitive 5-lipoxygenase and topo Learn More

3-O-Acetyl-beta-boswellic acid, Boswellia sp.
Product Number: B-1263

Product Name Price Qty
3-O-Acetyl-beta-boswellic acid, Boswellia sp. - 1x1 mg
$45.00
3-O-Acetyl-beta-boswellic acid, Boswellia sp. - 1x5 mg
$178.00
Boswellic acid derivative, which shows anti-tumor and anti-inflammatory activities. Potent non-redox, non-competitive 5-lipoxygenase and top Learn More

4-Bromo-A23187
Product Number: A-1130

Product Name Price Qty
4-Bromo-A23187 - 1x1 mg
$80.00
4-Bromo-A23187 - 1x5 mg
$240.00
Nonfluorescent calcium ionophore used as a calibration standard for determining cytoplasmic calcium ions by fluorescent probes. Learn More

5,5i difluoro-Bapta(AM)
Product Number: B-1085

Product Name Price Qty
5,5i difluoro-Bapta(AM) - 1x25 mg
$180.00

5,5i difluoro-Bapta(K+ Salt)
Product Number: B-1089

Product Name Price Qty
5,5i difluoro-Bapta(K+ Salt) - 1x100 mg
$425.00

A23187, Free Acid
Product Number: A-1020

Product Name Price Qty
A23187, Free Acid - 1x5 mg
$50.00
A23187, Free Acid - 1x10 mg
$75.00
A23187, Free Acid - 1x50 mg
$320.00
A widely used ionophore. It has the ability to increase the intracellular concentrations of cations and is widely used to increase the intra Learn More

A23187, Mixed Calcium-Magnesium Salt
Product Number: A-1128

Product Name Price Qty
A23187, Mixed Calcium-Magnesium Salt - 1x5 mg
$52.50
A23187, Mixed Calcium-Magnesium Salt - 1x10 mg
$84.00
Used in cell activation experiments when calcium dose-response data are not required. Molar ratio Ca:Mg~1:1. Learn More

Bapta(AM)
Product Number: B-1083

Product Name Price Qty
Bapta(AM) - 1x25 mg
$115.00
Bapta(AM) - 5x 25 mg
$500.00

Bapta(K+ Salt)
Product Number: B-1087

Product Name Price Qty
Bapta(K+ Salt) - 1x1 g
$100.00
Bapta(K+ Salt) - 5x 1 g
$445.00

Bapta-FF (AM)
Product Number: B-1093

Product Name Price Qty
Bapta-FF (AM) - 1x10 mg
$126.00
Bapta-FF (AM) - 5x 10 mg
$565.00

Bapta-FF (free acid)
Product Number: B-1091

Product Name Price Qty
Bapta-FF (free acid) - 1x10 mg
$126.00
Bapta-FF (free acid) - 5x 10 mg
$565.00

Calmodulin, Porcine
Product Number: C-1431

Product Name Price Qty
Calmodulin, Porcine - 1x1 mg
$60.00
Mammalian calmodulin isolated from porcine brain is suitable for applications requiring active pure calmodulin. Learn More

Calmodulin, Porcine, Biotinylated
Product Number: C-1433

Product Name Price Qty
Calmodulin, Porcine, Biotinylated - 1x100 ug
$185.00
Biotinylated porcine brain calmodulin using NHS ester activated biotin with an 8 atom spacer arm. Learn More

Calmodulin, Porcine, Fluorescein
Product Number: C-1435

Product Name Price Qty
Calmodulin, Porcine, Fluorescein - 1x100 ug
$185.00
FITC labeled mammalian calmodulin. Learn More

Calmodulin, Porcine, Immobilized Agarose
Product Number: C-1439

Product Name Price Qty
Calmodulin, Porcine, Immobilized Agarose - 1x2 mL
$300.00
Mammalian calmodulin immobilized to aldehyde activated agarose at 1 mg per mL. Coupled at 5 mg per mL and useful for pull down experiments a Learn More

Calmodulin, Porcine, Rhodamine
Product Number: C-1437

Product Name Price Qty
Calmodulin, Porcine, Rhodamine - 1x100 ug
$185.00
Mammalian calmodulin labeled with NHS ester of rhodamine. Learn More

Calmodulin, Porcine, Thiolyated
Product Number: C-1438

Product Name Price Qty
Calmodulin, Porcine, Thiolyated - 1x100 ug
$180.00
Mammalian calmodulin isolated from porcine brain is suitable for applications requiring active pure calmodulin. SH GROUP/Protein Ratio: C Learn More

Calmodulin, Wheat (Triticum aestivum) & Porcine, Immobilized High Loading;
Product Number: C-1441

Product Name Price Qty
Calmodulin, Wheat (Triticum aestivum) & Porcine, Immobilized High Loading; - 1x200 μL
$245.00
Calmodulins immobilized via SH (wheat germ) and amino groups (porcine) to epoxy resin allowing multiple orientations of bound calmodulin for Learn More

Calmodulin, Wheat (Triticum aestivum), Biotinylated
Product Number: C-1423

Product Name Price Qty
Calmodulin, Wheat (Triticum aestivum), Biotinylated - 1x50 ug
$250.00
Wheat germ (Triticum aestivum) calmodulin (CaM) sequence is unique in that it contains cysteine at residue position 26 (Cys26). In contrast Learn More

Calmodulin, Wheat (Triticum aestivum), Fluorescein
Product Number: C-1425

Product Name Price Qty
Calmodulin, Wheat (Triticum aestivum), Fluorescein - 1x50 ug
$250.00
Wheat germ (Triticum aestivum) calmodulin (CaM) sequence is unique in that it contains cysteine at residue position 26 (Cys26). In contrast Learn More

Calmodulin, Wheat (Triticum aestivum), Rhodamine
Product Number: C-1427

Product Name Price Qty
Calmodulin, Wheat (Triticum aestivum), Rhodamine - 1x50 ug
$250.00
Wheat germ (Triticum aestivum) calmodulin (CaM) sequence is unique in that it contains cysteine at residue position 26 (Cys26). In contrast Learn More

Calmodulin-SH, Wheat (Triticum aestivum)
Product Number: C-1421

Product Name Price Qty
Calmodulin-SH, Wheat (Triticum aestivum) - 1x250 ug
$60.00
Calmodulin-SH, Wheat (Triticum aestivum) - 1x1 mg
$160.00
Wheat germ (Triticum aestivum) calmodulin (CaM) sequence is unique in that it contains cysteine at residue position 26 (Cys26). In contrast Learn More

Calmodulin-SH, Wheat (Triticum aestivum), Immobilized High Loading
Product Number: C-1429

Product Name Price Qty
Calmodulin-SH, Wheat (Triticum aestivum), Immobilized High Loading - 1x200 ul
$250.00
Wheat germ (Triticum aestivum) calmodulin (CaM) sequence is unique in that it contains cysteine at residue position 26 (Cys26). Wheat germ Learn More

Coelenterazine
Product Number: C-1212

Product Name Price Qty
Coelenterazine - 1x50 μg
$94.50
Cell permeable, very sensitive and specific chemiluminescence probe of the superoxide anion and peroxynitrite. When oxidized by oxygen it il Learn More

Coelenterazine cp
Product Number: C-1275

Product Name Price Qty
Coelenterazine cp - 1x50 μg
$75.00
Coelenterazine cp - 1x1 mg
$785.00

Coelenterazine f
Product Number: C-1277

Product Name Price Qty
Coelenterazine f - 1x50 μg
$75.00
Coelenterazine f - 1x1 mg
$785.00
A highly sensitive and specific intracellular luminophore that is useful for measuring changes in superoxide and Ca2+ levels in cells transf Learn More

Coelenterazine fcp
Product Number: C-1279

Product Name Price Qty
Coelenterazine fcp - 1x50 μg
$75.00
Coelenterazine fcp - 1x1 mg
$785.00

Coelenterazine hcp
Product Number: C-1281

Product Name Price Qty
Coelenterazine hcp - 1x50 μg
$75.00
Coelenterazine hcp - 1x1 mg
$785.00
A highly sensitive and a specific intracellular luminophore that is useful for measuring changes in superoxide and Ca2+ levels in cells tran Learn More

Coelenterazine I
Product Number: C-1283

Product Name Price Qty
Coelenterazine I - 1x50 μg
$75.00

Coelenterazine ip
Product Number: C-1285

Product Name Price Qty
Coelenterazine ip - 1x50 μg
$75.00
Coelenterazine ip - 1x1 mg
$785.00

Coelenterazine n
Product Number: C-1287

Product Name Price Qty
Coelenterazine n - 1x50 μg
$75.00
Coelenterazine n - 1x1 mg
$785.00
An intracellular luminophore that is useful for measuring changes in superoxide and Ca2+ levels (in millimolar amounts for relatively longer Learn More

Coelenterazine Sampler Kit
Product Number: C-1291

Product Name Price Qty
Coelenterazine Sampler Kit - 1x1 Kit
$275.00

Coelenterazine, 2-methyl
Product Number: C-1289

Product Name Price Qty
Coelenterazine, 2-methyl - 1x50 μg
$55.00
Coelenterazine, 2-methyl - 1x1 mg
$175.00

Cyclopiazonic acid, Penicillium cyclopium
Product Number: C-1025

Product Name Price Qty
Cyclopiazonic acid, Penicillium cyclopium - 1x10 mg
$75.00
Cyclopiazonic acid, Penicillium cyclopium - 1x50 mg
$297.00
Reversible inhibitor of endoplasmic reticulum Ca2+ ATPase. Does not increase IP3 levels. Learn More

Cytochalasin D, Zygusporium mansonii
Product Number: C-1070

Product Name Price Qty
Cytochalasin D, Zygusporium mansonii - 1x1 mg
$65.00
Cytochalasin D, Zygusporium mansonii - 1x5 mg
$258.00
A fungal metabolite that acts as a potent inhibitor of actin filament and contractile microfilaments. Also shown to protect Hippocampal neur Learn More

D-myo-Ins(1,4,6)P3.3K
Product Number: I-1048

Product Name Price Qty
D-myo-Ins(1,4,6)P3.3K - 1x100 μg
$70.00
D-myo-Ins(1,4,6)P3.3K - 1x1 mg
$315.00

D-myoIns(2,3,5)P3.3K
Product Number: I-1049

Product Name Price Qty
D-myoIns(2,3,5)P3.3K - 1x100 μg
$70.00
D-myoIns(2,3,5)P3.3K - 1x1 mg
$315.00

DCG-IV
Product Number: D-1296

Product Name Price Qty
DCG-IV - 1x1mg
$50.00
DCG-IV - 1x5mg
$150.00
Presynaptic depressant. Product is highly potent group II mGluR agonist Learn More

Diltiazem.HCl
Product Number: D-1159

Product Name Price Qty
Diltiazem.HCl - 1x1 g
$55.00
Diltiazem.HCl - 1x5 g
$220.00
Blocks slow, or L-type Ca2+ channels; regulates Ca2+ release from intracellular stores in neutrophils. Learn More

FFP-18(AM)
Product Number: F-1052

Product Name Price Qty
FFP-18(AM) - 1x500 μg
$150.00
FFP-18(AM) - 10x 50 μg
$195.00
Cell-permeable, acetoxymethyl ester (AM) derivative of FFP-18 useful as a near-membrane calcium indicator. Excitation max.: 364 nm (low Ca2+ Learn More

FIP-18(AM)
Product Number: F-1054

Product Name Price Qty
FIP-18(AM) - 1x500 ug
$150.00
FIP-18(AM) - 10x 50ug
$195.00

Fura-2(AM)
Product Number: F-1040

Product Name Price Qty
Fura-2(AM) - 1x1 mg
$135.00
Fura-2(AM) - 20x 50 μg
$189.00
Cell permeable Fluorescent Ca2+ indicator. Hydrolysis by non-specific esterases traps the indicator in the cytosol. Learn More

Fura-2(K+ Salt)
Product Number: F-1042

Product Name Price Qty
Fura-2(K+ Salt) - 1x1 mg
$115.00

Fura-2FF(AM)
Product Number: F-1044

Product Name Price Qty
Fura-2FF(AM) - 1x500 μg
$185.00
Fura-2FF(AM) - 10x 50 μg
$195.00
Cell-permeable acetoxymethyl ester derivative of FURA-2FF with spectral properties similar to Fura-2FF. Learn More

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