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Product Description
StemRegenin 1, HCl is a cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs).
Culture of HSCs with SR1 led to a 50-fold increase in cells expressing CD34 and a 17-fold increase in cells that retain the ability to engraft immunodeficient mice.
In the absence of cytokines, StemRegenin 1 did not induce proliferation, and at concentrations above 1 µM, it inhibits proliferation.
Additional Information
| Product Number | S-2136 |
| CAS # | 1227633-49-9 |
| Chemical Name | 4-(2-((2-Benzo[b]thiphen-3-yl)-9-isopropyl-9H-purin-6-yl)amino)phenol hydrochloride; SR1 |
| Chemical Formula | C₂₄H₂₃N₅OS.HCl |
| Appearance | White solid |
| Molecular Weight | 466.0 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (~ 10 mM) |
| Storage Temp | -20°C |
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All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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