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Signal Transduction Inhibitors
Image courtesy of Public Library of Science publication Derivation of High Purity Neuronal Progenitors from Human Embryonic Stem Cells from researchers at Reeve-Irvine Research Center, Sue and Bill Gross Stem Cell Research Center University of California Irvine, California Stem Cell, Inc. Irvine, California, and Pfizer Regenerative Medicine, Cambridge, Massachusetts. AG Scientific’s Rolipram was used to reduce neuronal damage prior to and following transplant of hNP cells into rodent spinal cord.
AG Scientific: A leader in inhibitors
Invasive proteases can contaminate research samples and slow or halt research progress, rendering time-consuming and expensive work useless. Protease inhibitor cocktails are a unique series of enzyme inhibitors that knock out specific proteases to avoid peptide bond hydrolysis and subsequent protein destruction. AG Scientific maintains a large selection of standard inhibitor cocktails in stock, as well as the ability to prepare custom formulations, our most popular are:
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Protease Inhibitor Cocktail III is a specially formulated cocktail of six protease inhibitors with broad specificity for the inhibition of aspartic, cysteine and serine proteases as well as aminopeptidases.
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Protease Inhibitor Cocktail IV specially formulated cocktail of four protease inhibitors with broad specificity for the inhibition of serine, cysteine, aspartic and metallo-proteases.
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Bestatin is an aminopeptidase inhibitor.
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Leupeptin a reversible inhibitor of serine and cysteine proteases. Often used for the inhibition of plasmin, trypsin, papain, kallikrein and cathepsin B.
AG Scientific delivers quality assured reagents directly to scientists, from small-scale to bulk orders. Our leadership in bulk supply allows us to provide custom product packaging and create multiple product forms. We offer “just in time” delivery, private labeling, and custom formulations for specific research needs.
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