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Protein Phosphatases

Protein Phosphatases

AG Scientific: A leader in protein phosphatases

Phosphatase inhibitors cocktails instantaneously inhibit the following: alkaline phosphatases,protein phosphatases 1, protein phosphatases 2A, protein tyrosine phosphatase, acid phosphatases, alkaline phosphatases, serine/theronine phosphatases, alkaline phosphatases.

Phosphatases remove phosphate groups from monophosphate esters, leaving a free hydroxyl group. Phosphatases play an important role in many signal transduction pathways, as the addition or removal of a phosphate group can activate or de-activate an enzyme, or allow a particular protein-protein interaction. Medical applications of various types of phosphatases range from regulation of gene expression to diagnostic testing for a variety of disorders including anemia, liver function, and various types of cancers.

For a downloadable summary of AG Scientific's Protease & Phosphatase Inhibitor cocktails, click here!

AG Scientific delivers quality assured reagents directly to scientists, from small-scale to bulk orders. Our leadership in bulk supply allows us to provide custom product packaging and create multiple product forms. We offer “just in time” delivery, private labeling, and custom formulations for specific research needs.

FREE REVIEW ARTICLES

Protein phosphatases and the regulation of mitosis, Francis A. Barr, Paul R. Elliott, et al. Protein phosphatases and the regulation of mitosis. J. Cell Sci, 2011; 124: 2323 - 2334.

Cellular prostatic acid phosphatase: a protein tyrosine phosphatase involved in androgen-independent proliferation of prostate cancer, Suresh Veeramani, Ta-Chun Yuan, et al. Cellular prostatic acid phosphatase: a protein tyrosine phosphatase involved in androgen-independent proliferation of prostate cancer. Endocr. Relat. Cancer, 2005; 12: 805 - 822.

Protein tyrosine phosphatases and signalling, Andrew W Stoker. Protein tyrosine phosphatases and signalling. J. Endocrinol, 2005; 185: 19 - 33.

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Product Number	G-1247
CAS #	CAS [667463-62-9]
Chemical Name	(2′Z,3′E)-6-Bromoindirubin-3′-oxime
Chemical Formula	C₁₆H₁₀BrN₃O₂
Alternative Name	6BIO , GSK-3 Inhibitor \| CAS [667463-62-9] \| A.G. Scientific
Appearance	Dark Red to Purple solid.
Molecular Weight	M.W.356.2
Preparation	Packaged under inert gas.
Purity	Purity:≥98%
Solubility	DMSO
Storage Temp	-20º C

COA Documentation: G-1247, B1968 6BIO , GSK-3 Inhibitor Product Number: G-1247
Price	Price	Qty	Add to Cart
1x1 mg	$50.00

Product Number	P-1551
Appearance	Lyophilized
Solubility	Soluble in 1ml H₂0 to obtain 1 ml stock solution
Storage Temp	-20C

MSDS Documentation: P-1551, PIA, MSDS COA Documentation: P-1551, B1579 P-1551, C1097 A custom cocktail for optimum inhibition of calciuPIA 100x Protease Inhbitor A Cocktail \| AG Scientific Product Number: P-1551
Price	Price	Qty	Add to Cart
1x1 vial	$45.00

Product Number	C-1031
CAS #	CAS [101932-71-2]
Chemical Formula	C₅₀H₈₁N₄O₁₅P
Appearance	Oil
Molecular Weight	M.W. 1009.2
Purity	Purity: >98%
Solubility	Soluble in DMSO, Ethanol, DMF.
Storage Temp	-20°C

COA Documentation: C-1031, Calyculin A, A9703A C-1031, Calyculin A, B1264A Calyculin A, Discodermia calyx Product Number: C-1031
Price	Price	Qty	Add to Cart
1x25 ug	$132.00
1x100 ug	$368.00

Product Number	A-1304
Alternative Name	Cartilage Oligomeric Matrix Protein: Angiopoietin-1, Human, Recombinant
Appearance	Liquid. 0.2um-filtered solution in PBS containing 0.01% CHAPS.
Molecular Weight	<0.1 Euug protein (LAL test, BioWhittaker)
Preparation	Working aliquots are stable for up to 3 months when stored at -20°C.
Purity	Purity: ≥90% by SDS-PAGE
Storage Temp	-20°C

COMP, Rat: Angiopoietin-1, Soluble, Human, Recombinant Product Number: A-1304
Price	Price	Qty	Add to Cart
1x10 ug	$438.00
1x50 ug	$1,120.00

Product Number	C-1199
CAS #	CAS [59865-13-3]
Chemical Formula	C₆₂H₁₁₁N₁₁O₁₂
Alternative Name	Ciclosporin, Cyclosporin A, Ramihyphin A
Appearance	White powder
Merck Index	Merck Index: 13.2781.2001
Molecular Weight	M.W. 1202.6
Purity	Purity: ≥98%
Solubility	Soluble in DMSO (25mg/ml), methanol, 100% ethanol (25mg/ml), or acetone. Insoluble in water
Storage Temp	-20°C

COA Documentation: C-1199, A8587, r01 Cyclosporin A, Fusarium solani Product Number: C-1199
Price	Price	Qty	Add to Cart
1x100 mg	$55.00
1x500 mg	$215.00

Product Number	D-1306
CAS #	[440100-64-1]
Chemical Formula	C₁₇H₂₄N₆O1/2 H₂O
Alternative Name	DPP IV Inhibitor, dipeptidyl aminopeptidase IV inhibitor, CD26 inhibitor, glycoprotein GP110 inhibitor, glycylproline aminopeptidase inhibitor, Tp103 inhibitor, X-PDAP inhibitor, THAM inhibitor
Appearance	Light Brown Solid
Molecular Weight	328.4 is anhydrous molecular weight. Refer to label for lot specific hydration and molecular weight. Current product is 337.42
Purity	≥98%
Solubility	Soluble in DMSO or Ethanol
Storage Temp	+4°C

Dipeptidylpeptidase IV Inhibitor, K579 Product Number: D-1306
Price	Price	Qty	Add to Cart
1x10 mg	$185.00
1x50 mg	$780.00

Product Number	e-2044
CAS #	[51798-45-9]
Chemical Formula	C₂₁H₃₆N₈O₇
Appearance	Yellow Solid
Molecular Weight	512.6
Purity	determined by activity.
Storage Temp	-20C

MSDS Documentation: E-2044, Elastatinal, MSDS COA Documentation: E-2044, C1162 E-2044, C1163 E-2044, C1164 E-2044, C1164A Elastatinal Product Number: e-2044
Price	Price	Qty	Add to Cart
1x5 mg	$70.00
1x25 mg	$285.00

Product Number	F-1038
Chemical Name	Phosphotrienin, CI-920
Chemical Formula	C₁₉H₂₆O₉PNa
Appearance	Colorless Solid
Molecular Weight	M.W. 452.4
Preparation	Packaged under Argon. Use Fresh Solution.
Purity	Purity: >98%
Solubility	Soluble in Water, Methanol or Ethanol.
Storage Temp	-20°C

COA Documentation: F-1038, B1209 Fostriecin, Streptomyces Pulveraceous subsp. Fostreus Product Number: F-1038
Price	Price	Qty	Add to Cart
1x10 μg	$160.00

Product Number	F-1160
CAS #	[82956-11-4]
Chemical Formula	C21H25N5O8S2
Alternative Name	FUT-175, Nafamostat Mesylate
Appearance	White to off white
Merck Index	14, 6350
Molecular Weight	539.6
Purity	>98%
RTECS	DG2736000
Solubility	Soluble in DMSO or water

MSDS Documentation: F-1160, Futhan, MSDS COA Documentation: F-1160, B1683 F-1160, C1201 F-1160, C1202 Futhan Product Number: F-1160
Price	Price	Qty	Add to Cart
1x10 mg	$70.00
1x50 mg	$285.00

Product Number	C-1543
Chemical Name	SPECIES CROSS-REACTIVITY: Human, APPLICATIONS/DILUTIONS: IF (2.0 ug/ml), IP (1.0 ug/sample), Western blot (2.0 ug/ml)
Appearance	100 ug purified IgG1 with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA.
Solubility	SOURCE: RBF/DnJ mice were immunized with recombinant human cdc25C fragment corresponding to amino acids 1-258 and fusing the splenocytes with NS-1 mouse myeloma cells. Epitope is known to be between amino acid residues 222-246.
Storage Temp	-20º C

Mouse Monoclonal Antibody-cdc25c (Clone TC-113) Product Number: C-1543
Price	Price	Qty	Add to Cart
1x100 ug	$250.00

Product Number	C-1533
Chemical Name	SPECIES CROSS-REACTIVITY: Human, APPLICATIONS/DILUTIONS: IF (2.5 ug/ml), IP (1.0 ug/sample), Western blot (1.0 ug/ml).
Appearance	100 ug purified IgG1 with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA.
Solubility	SOURCE: RBF/DnJ mice were immunized with recombinant human cdc25C fragment corresponding to amino acids 1-258 and fusing the splenocytes with NS-1 mouse myeloma cells. Epitope is known to be between amino acid residues 211-246.
Storage Temp	-20ºC

Mouse Monoclonal Antibody-cdc25c (Clone TC-19) Product Number: C-1533
Price	Price	Qty	Add to Cart
1x100 ug	$250.00

Product Number	C-1563
Chemical Name	SPECIES CROSS-REACTIVITY: Human, primate, rat. No cross-reactivity with mouse. APPLICATIONS/DILUTIONS: IP (1ug/sample), Western blot (2.5 ug/ml).
Appearance	100 ug purified IgG2a with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA.
Solubility	SOURCE: Mice were immunized with recombinant human cdc6 protein and fusing the splenocytes with NS1/Ag4-1 mouse myeloma cells.
Storage Temp	-20º C

Mouse Monoclonal Antibody-cdc6 (Clone 6-36) Product Number: C-1563
Price	Price	Qty	Add to Cart
1x100 ug	$250.00

Product Number	O-1030
CAS #	CAS [209266-80-8]
Chemical Name	9,10-Deepithio-9,10-didehydroacanthifolicin, Halochondrine A. Na, Halochondrine A sodium salt
Chemical Formula	C₄₄H₆₇O₁₃.Na
Appearance	White Solid
Melting Point	MP: 164-166°C
Merck Index	Merck Index: 16.6891.2001
Molecular Weight	M.W. 828.00
Purity	Purity: >98%
Solubility	Soluble in DMSO, Ethanol, and Water.
Storage Temp	-20°C

COA Documentation: O-1030, B1011 O-1030, B1229 O-1030, C1342 O-1030, C1366 Okadaic Acid Sodium Salt, Prorocentrum concavum Product Number: O-1030
Price	Price	Qty	Add to Cart
1x25 μg	$45.00
1x50 ug	$65.00
1x100 μg	$103.00

Product Number	O-1024
CAS #	CAS [78111-17-8]
Chemical Name	9,10-Deepithio-9,10-didehydroacanthifolicin, Halochondrine A
Chemical Formula	C₄₄H₆₈O₁₃
Appearance	White Crystalline Solid
Melting Point	MP: 164-166°C
Merck Index	Merck Index: 13.6891.2001
Molecular Weight	M.W. 805.0
Purity	Purity:≥98% (HPLC)
Solubility	Soluble in DMSO, 100% ethanol or methanol (1mg/ml).
Storage Temp	-20°C

COA Documentation: O-1024, A9183 O-1024, B1185 Okadaic acid, Prorocentrum concavum, High Purity Product Number: O-1024
Price	Price	Qty	Add to Cart
1x50 μg	$70.00
1x100 μg	$103.00
1x1 mg	$830.00

Product Number	O-1026
CAS #	CAS [155716-06-6]
Chemical Name	9,10-Deepithio-9,10-didehydroacanthifolicin . Na (high purity)
Chemical Formula	C₄₄H₆₈O₁₃.NH₃
Alternative Name	Halochondrine A . Ammonium salt (high purity)
Appearance	White to off-white solid
Melting Point	MP: 164-166°C
Molecular Weight	M.W. 822.0
Purity	Purity: ≥98% (HPLC)
Solubility	Soluble in (100%) ethanol, DMSO,methanol, acetone, ethyl acetate or destilled water.
Storage Temp	-20°C

COA Documentation: O-1026, A8731 O-1026, B1960 Okadaic acid.Ammonium Salt, Prorocentrum concavum Product Number: O-1026
Price	Price	Qty	Add to Cart
1x25 μg	$45.00
1x50 ug	$65.00
1x100 μg	$103.00

Product Number	O-1028
CAS #	CAS [155751-72-7]
Chemical Name	9,10-Deepithio-9,10-didehydroacanthifolicin . sodium salt (high purity)
Chemical Formula	C₄₄H₆₇O₁₃.K
Alternative Name	Halochondrine A . potassium salt (high purity)
Appearance	White Solid
Melting Point	MP: 164-166°C
Merck Index	Merck Index: 13.6891.2001
Molecular Weight	M.W. 844.1
Purity	Purity: >98%
Solubility	Soluble in DMSO, Ethanol, and Water.
Storage Temp	-20°C

COA Documentation: O-1028, C1047 O-1028, B1959 O-1028, C1238 O-1028, C1324 Okadaic acid.Potassium Salt, Prorocentrum concavum Product Number: O-1028
Price	Price	Qty	Add to Cart
1x25 ug	$45.00
1x50 ug	$70.00
1x100 ug	$103.00

Product Number	P-1517
Appearance	Clear colorless liquid. In 1ml DMSO.
Purity	Suitable for use as Phosphatase Inhibitor
Solubility	Recommended usage is 100-fold dilution
Storage Temp	-20°C

MSDS Documentation: P-1517, PHOSPHATASE INHIBITOR COCKTAIL I, MSDS COA Documentation: P-1517, B1912 P-1517, C1180 P-1517, D1030 Phosphatase Inhibitor Cocktail I Product Number: P-1517
Price	Price	Qty	Add to Cart
1x1 vial	$38.00

Product Number	P-1518
Appearance	White Lyophilized Solid
Solubility	Reconstitute each vial with 1 ml H2O to obtain a 1 ml stock solution. Recommended usage is a 100-fold dilution.
Storage Temp	-20°C

MSDS Documentation: P-1518, MSDS COA Documentation: P-1518, C1154 P-1518, C1181 P-1518, C1304 P-1518, C1346 Phosphatase Inhibitor Cocktail II Product Number: P-1518
Price	Price	Qty	Add to Cart
1x1 vial	$38.00

Product Number	P-1510
Appearance	White lyophilized solid.
Purity	suitable for use as Protease Inhibitors
Solubility	Reconstitute each vial with 1ml water (H2O) to obtain a 100X concentrated stock solution. Dilute with 100ml solution to achieve 1X stock solution.
Storage Temp	-20C

COA Documentation: P-1510, C1029 P-1510, C1237 Protease Inhibitor Cocktail I Product Number: P-1510
Price	Price	Qty	Add to Cart
1x1 vial	$25.00

Product Number	P-1512
Appearance	Liquid, in 1ml DMSO
Purity	suitable for use as Protease Inhibitors.
Storage Temp	-20°C

COA Documentation: P-1512, C1030 P-1512, C1226 P-1512, C1367 Protease Inhibitor Cocktail III Product Number: P-1512
Price	Price	Qty	Add to Cart
1x1 Vial	$38.00

Product Number	P-1514
Appearance	White Lyophilized Solid
Solubility	Reconstitute each vial with 1 ml H2O to obtain a 100X concentrated stock solution. Dilute with 100ml solution to achieve 1X stock solution.
Storage Temp	-20°C

COA Documentation: P-1514, B1911 P-1514, C1048 P-1514, C1236 P-1514, D1079 Protease Inhibitor Cocktail V, EDTA-Free Product Number: P-1514
Price	Price	Qty	Add to Cart
1x1 vial	$25.00

Product Number	P-1554
Appearance	White Lyophilized Solid
Storage Temp	-20°C

COA Documentation: P-1554, D1015 P-1554, C1117 P-1554, C1210 P-1554, C1293 Protease Inhibitor Cocktail VI, EDTA-Free Product Number: P-1554
Price	Price	Qty	Add to Cart
1x1 vial	$32.00

Product Number	P-1548
Appearance	Clear Colorless Solution
Purity	Suitable for use as Protease Inhibitors.
Solubility	Supplied as a liquid in 1 ml DMSO. Add to water, aqueous buffer or directly to extraction media.
Storage Temp	-20°C

COA Documentation: P-1548, B1523 P-1548, C1312 Protease Inhibitor Cocktail VIII Product Number: P-1548
Price	Price	Qty	Add to Cart
1x1 ml	$54.00

Product Number	S-2072
CAS #	CAS [405060-95-9]
Chemical Formula	C₂₁H₂₀Cl₃N₄OS
Appearance	White to off-white powder.
Molecular Weight	M.W. 479.8
Solubility	Soluble in DMSO (10mg/ml).
Storage Temp	-20°C

COA Documentation: S-2072, A9154 Salubrinal Product Number: S-2072
Price	Price	Qty	Add to Cart
1x1 mg	$32.00
1x5 mg	$100.00

COA Documentation: P-1516, B1918 P-1516, B1733 P-1516, C1235 Serine Protease Inhibitor Cocktail I Product Number: P-1516
Price	Price	Qty	Add to Cart
1x1 vial	$59.00

TCEP.HCl Product Number: T-1180
Price	Price	Qty	Add to Cart
1x1 g	$44.00
1x5 g	$195.00

YPAC Cocktail Set (1000X), Sterile-Filtered Product Number: S-2138
Price	Price	Qty	Add to Cart
1x1 ml	$225.00
1x5 ml	$785.00
5x1 ml	$835.00

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Protein Phosphatases

AG Scientific: A leader in protein phosphatases

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Product Number	P-1516
Appearance	White Lyophilized Solid
Solubility	Reconstitute each vial with 1 ml H2O to obtain a 100X concentrated stock solution.
Storage Temp	-20°C.

Product Number	T-1180
CAS #	51805-45-9
Chemical Name	tris(2-Carboxyethyl)phosphine.hydrochloride
Chemical Formula	C₉H₁₅O₆P.HCl
Appearance	White Crystalline Solid
Molecular Weight	286.65
Purity	>98%, NMT by elemental analysis
Solubility	Soluble in Water, 50mg/ml.
Storage Temp	+4°C

Product Number	S-2138
CAS #	See under the individual product
Chemical Name	See under the individual product
Chemical Formula	See under the individual product
Alternative Name	StemBoost
Appearance	Liquid
Molecular Weight	See under the individual product
Purity	≥97% by HPLC
Solubility	DMSO
Storage Temp	-20°C