![Trichostatin A | CAS [ 58880-19-6 ] | inhibits Histone deacetylase & Immunosuppressant | Trichostatin A is an antifungal antibiotic derived From Streptomycs Platensis. Inhibits Histone deacetylase. Blocks cell cycle progression at the GI phase in Hela cel](http://www.agscientific.com/media/catalog/product/cache/1/thumbnail/56x/5e06319eda06f020e43594a9c230972d/T/-/T-1052_250x500_2.jpg "Trichostatin A | CAS [ 58880-19-6 ] | inhibits Histone deacetylase & Immunosuppressant | Trichostatin A is an antifungal antibiotic derived From Streptomycs Platensis. Inhibits Histone deacetylase. Blocks cell cycle progression at the GI phase in Hela cel")
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Product Description
From Streptomycs Platensis. Trichostatin A inhibits Histone deacetylase. Trichostatin A blocks cell cycle progression at the GI phase in Hela cells. Trichostatin A also demonstrates immunosuppressive activity. ** Bulk stock available, inquire for pricing
Seeking published researchers utilizing our Trichostatin A product? Hit the hot link for the full paper.
- METABOLISM: Sodium Butyrate Stimulates Expression of Fibroblast Growth Factor 21 in Liver by Inhibition of Histone Deacetylase 3, Huating Li, Zhanguo Gao, et al., Diabetes, Apr 2012; 61: 797 - 806.
- DEVELOPMENT/PLASTICITY/REPAIR: Epigenetic Enhancement of BDNF Signaling Rescues Synaptic Plasticity in Aging, Yan Zeng, Miao Tan, et al., J. Neurosci., Dec 2011; 31: 17800 - 17810.
- BEHAVIORAL/SYSTEMS/COGNITIVE: Histone Deacetylase Inhibitors Enhance Memory and Synaptic Plasticity via CREB: CBP-Dependent Transcriptional Activation, Christopher G. Vecsey, et al., Neurosci., Jun 2007; 27: 6128 - 6140.
- RETINAL CELL BIOLOGY: Histone Deacetylase Inhibition–Mediated Differentiation of RGC-5 Cells and Interaction with Survival, Brandon R. Schwechter, Lucia E. Millet, and Leonard A. Levin, Invest. Ophthalmol. Vis. Sci., Jun 2007; 48: 2845 - 2857
Additional Information
COA Documentation: |
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| Product Number | T-1052 |
| CAS # | CAS [58880-19-6] |
| Chemical Formula | C17H22N2O3 |
| Alternative Name | Trichostatin A | TSA CAS# 58880-19-6 | Inhibits Histone deacetylase & cell cyle G1 |
| Appearance | White Powder |
| Molecular Weight | M.W. 302.4 |
| Preparation | Solutions stored at -20°C are good for 1- 2 months. |
| Purity | Purity: >98% |
| RTECS | RTECS: MI5215000 |
| Solubility | Soluble in DMSO and Ethanol. |
| Storage Temp | -20°C |
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