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Product Description
Specific cell permeable inhibitor. Potent cell permeable and metabolically stable specific inhibitor of hSIRT1 (IC50=98nM in vivo / IC50=38nM in vitro; compared to hSIRT2: IC50=19µM and hSIRT3: IC50=48 μM) with no effect on human histone deacetylases (HDACs) class I and class II, nor NAD glycohydrolase (IC50>100 μg). Inhibits the deacetylation of p53 (IC50=1 μM).
Additional Information
COA Documentation: |
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| Product Number | C-1445 |
| CAS # | CAS [49843-98-3] |
| Chemical Formula | C13H13ClN2O |
| Alternative Name | EX-527 |
| Appearance | White to Tan powder. |
| Molecular Weight | M.W. 248.7 |
| Purity | Purity: >95% |
| Solubility | Soluble in DMSO (10mg/ml). |
| Storage Temp | -20°C |
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All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
