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Compound 52

COMPOUND 52
Product Number: C-1553

        

Details

Potent, cell permeable and selective inhibitor of CDK1 (IC=340nM) the cell cycle -regulating kinase Cdc28p (IC=7M) and the related Pho85p kinase (IC=2M).

Additional Information

Alternate Name/Synonyms [2-(2-Hydroxyethylamino)-6-(3-choroanilino)-9-isopropylpurine]
Package ID Refrigerated
CHEMACX X1341277-4
Chemical name (IUPAC) 2-((6-((3-CHLOROPHENYL)AMINO)-9-ISOPROPYL-9H-PURIN-2-YL)AMINO)ETHANOL
HAZARD CLASS Not Applicable
INCHI InChI=1S/C16H19ClN6O/c1-10(2)23-9-19-13-14(20-12-5-3-4-11(17)8-12)21-16(18-6-7-24)22-15(13)23/h3-5,8-10,24H,6-7H2,1-2H3,(H2,18,20,21,22)
INDICATION Not Available
Soluble Soluble in DMSO or methanol.
MDL NUMBER MFCD02179196
Molecular Formula C16H19CIN6O
MP/BOILING POINT 587.7±60.0 °C at 760 mmHg
PACKING GROUP Not Applicable
Peptide sequence Not Applicable
SMILES CC(C)n1cnc2c1nc(nc2Nc3cccc(c3)Cl)NCCO
THERAPEUTIC AREA Not Available
UN #'S Not Applicable
USE Potent, cell permeable and selective inhibitor of CDK1
Product Number C-1553
CAS # 212779-48-1
Chemical Name [2-(2-Hydroxyethylamino)-6-(3-choroanilino)-9-isopropylpurine]
Chemical Formula C16H19CIN6O
Appearance White to Off White Solid
Molecular Weight 346.8
Purity 99%
RTECS Not Applicable
Solubility Soluble in DMSO or methanol.
Storage Temp -20°C

Compound 52