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Cytochalasin D- STRUCTURE-ANTI-FUNGAL-ACTIN FILAMENTS

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Cytochalasin D

CAS: 22144-77-0 Formula: C30H37NO6 MW: 507.63 Appearance: White Solid Purity: 97%
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C-1070 1 mg
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Cytochalasin D is a cell-permeable fungal toxin, 10-fold more effective than Cytochalasin B.Binds to barbed end of actin filaments, inhibiting the association and dissociation of subunits.Does not inhibit monosaccharide transport across cell membranes.Reported to exhibit antitumor activity, and induce apoptosis.

Additional Information

Synonyms Zygosporin A
Product # C-1070
CAS # 22144-77-0
Chemical Name (7S,13E,16S,18R,19E,21R)-21-(ACETYLOXY)-7,18-DIHYDROXY-16,18-DIMETHYL-10-PHENYL[11]CYTOCHALASA-6(12),13,19-TRIENE-1,17-DIONE
Formula C30H37NO6
MW 507.63
Appearance White Solid
Purity 97%
Solubility Soluble in 100% ethanol, acetone or ethyl acetate. Insoluble in water.
Melting Point 255-260°C
Boiling Point 712.1±60.0 °C at 760 mmHg
Storage Temp -20°C
Use Cytochalasin D is a member of the class of mycotoxins known as cytochalasins

Additional Information

Merck Index 12.2859.1996
MDL Number MFCD00077706
ChemACX X1009686-7
InChI InChI=1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9+,15-14+/t17-,18+,22-,23-,24+,25-,26+,29+,30+/m0/s1
SMILES C[C@H]1C/C=C/[C@H]2[C@@H](C(=C)[C@H]([C@@H]3[C@@]2([C@@H](/C=C/[C@@](C1=O)(C)O)OC(=O)C)C(=O)N[C@H]3Cc4ccccc4)C)O

Additional Information

GHS Pictograms
RTECS GZ4850000
UN #'S UN 1544
PACKING GROUP II
Handling Protect from Light Store in Tightly Sealed Vial Warning.Toxic.

Additional Information

msds 1 C-1070_C-1070,_Cytochalasin_D,_MSDS.pdf
Certificate of Analysis 1 C-1070_C-1070,_A9914.pdf

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Cytochalasin D

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