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Cytochalasin D- STRUCTURE-ANTI-FUNGAL-ACTIN FILAMENTS

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Cytochalasin D, Zygosporin A

CAS: 22144-77-0 Formula: C30H37NO6 MW: 507.63 Appearance: White Solid Purity: 97%
Hazardous

3

2

0

0

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C-1070 1 mg
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Cytochalasin D is a cell-permeable fungal toxin, 10-fold more effective than Cytochalasin B.Binds to barbed end of actin filaments, inhibiting the association and dissociation of subunits.

Does not inhibit monosaccharide transport across cell membranes. Cytochalasin D is reported to exhibit antitumor activity, and induce apoptosis.

Additional Information

Synonyms Zygosporin A
Product # C-1070
CAS # 22144-77-0
Chemical Name (7S,13E,16S,18R,19E,21R)-21-(ACETYLOXY)-7,18-DIHYDROXY-16,18-DIMETHYL-10-PHENYL[11]CYTOCHALASA-6(12),13,19-TRIENE-1,17-DIONE
Formula C30H37NO6
MW 507.63
Appearance White Solid
Purity 97%
Solubility Soluble in 100% ethanol, acetone or ethyl acetate. Insoluble in water.
Melting Point 255-260°C
Boiling Point 712.1±60.0 °C at 760 mmHg
Storage Temp -20°C
Use Cytochalasin D is a member of the class of mycotoxins known as cytochalasins

Additional Information

Merck Index 12.2859.1996
MDL Number MFCD00077706
ChemACX X1009686-7
InChI InChI=1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9+,15-14+/t17-,18+,22-,23-,24+,25-,26+,29+,30+/m0/s1
SMILES C[C@H]1C/C=C/[C@H]2[C@@H](C(=C)[C@H]([C@@H]3[C@@]2([C@@H](/C=C/[C@@](C1=O)(C)O)OC(=O)C)C(=O)N[C@H]3Cc4ccccc4)C)O

Additional Information

GHS Pictograms
RTECS GZ4850000
UN #'S UN 1544
PACKING GROUP II
Handling Protect from Light Store in Tightly Sealed Vial Warning.Toxic.

Additional Information

msds 1 C-1070_C-1070,_Cytochalasin_D,_MSDS.pdf
Certificate of Analysis 1 C-1070_C-1070,_A9914.pdf

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Cytochalasin D, Zygosporin A

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