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Etoposide

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Etoposide

CAS: 33419-42-0 Formula: C29H32O13 MW: 588.6 Appearance: White to Off-White Solid Purity: 97%
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E-2004 100 mg
$87.50
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500 mg
$341.47
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Topoisomerase II inhibitor. Anti-tumor reagent. Widely used apoptosis inducer by FasL. Semisynthetically derived frompodophyllotoxin.

Additional Information

Synonyms VP-16-213
Product # E-2004
CAS # 33419-42-0
Chemical Name 4-Desmethylepipodophyllotoxin 9-(4,6-0-ethylidene)-½‚²- D-glucopyranoside
Formula C29H32O13
MW 588.6
Appearance White to Off-White Solid
Purity 97%
Solubility Soluble in DMSO, DMF, Ethyl ether,Chloroform:methanol (1:1). Slightly soluble in methanol or acetone;insoluble in water
Melting Point 236-251 °C
Boiling Point 798.1 °C at 760 mmHg
Storage Temp -20°C
Therapeutic Area Oncological Disorders
Use Inhibits DNA synthesis via topoisomerase II inhibition used as a form of chemotherapy for cancers

Additional Information

MDL Number MFCD00869325
ChemACX X1004425-4
InChI InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1
SMILES C[C@@H]1OC[C@@H]2[C@@H](O1)[C@@H]([C@H]([C@@H](O2)O[C@@H]3c4cc5c(cc4[C@H]([C@@H]6[C@@H]3COC6=O)c7cc(c(c(c7)OC)O)OC)OCO5)O)O

Additional Information

GHS Pictograms
RTECS KC0190000
Handling TOXIC.Store in Tightly Sealed Vial Protect from Light Protect from Moisture. Possible Carcinogen. Store DMSO solutions short term 4C, long term at -20C.

Additional Information

Certificate of Analysis 1 E-2004, E1066B.pdf
Certificate of Analysis 2 E-2004, E1066A.pdf

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Etoposide

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