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Dorsomorphin, AMPK Inhibitor

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Dorsomorphin, AMPK Inhibitor

CAS: 866405-64-3 Formula: C24H25N5O MW: 399.5 Appearance: Yellow Solid Purity: 99%
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D-1310 5 mg
$121.78
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Cell-permeable pyrrazolopyrimidine derivative that inhibits AMP kinase in an ATP-competitive manner. It displays no significant inhibition of ZAPK, SYKK, PKCT, PKA and JAK3. Decreases food intake in mice and inhibits the effects of AICAR and metformin. IT has been shown to inhibit BMP type I receptors ALK2, ALK3 and ALK6.

Additional Information

Synonyms BML-275, Compound C, AMPK INHIBITOR
Product # D-1310
CAS # 866405-64-3
Chemical Name 6-[4-(2-Piperidin-1-yl)-ethoxy)- phenyl)]-3-pyridin-4-yl- pyrazolo[1,5-a]-pyrimidine
Formula C24H25N5O
MW 399.5
Appearance Yellow Solid
Purity 99%
Solubility Soluble in DMSO
Melting Point 244.93 °C
Storage Temp -20°C
Therapeutic Area Neurological Disorders
Use A potent inhibitor of AMPK

Additional Information

MDL Number MFCD08705402
ChemACX X1561649-0
InChI InChI=1S/C24H25N5O/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20/h4-11,16-18H,1-3,12-15H2
SMILES C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3

Additional Information

GHS Pictograms
Handling Protect from moisture.

Additional Information

Certificate of Analysis 1 D-1310, E1312C.pdf
Certificate of Analysis 2 D-1310, E1312B.pdf
Certificate of Analysis 3 D-1310, E1312A.pdf

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Dorsomorphin, AMPK Inhibitor

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