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Dorsomorphin | Compound C | CAS# 866405-64-3 | AMPK Inhibitor. Also inhibits BMP type I receptors ALK2, ALK3 and ALK6

DORSOMORPHIN, AMPK INHIBITOR
Product Number: D-1310

        

Details

Cell-permeable pyrrazolopyrimidine derivative that inhibits AMP kinase in an ATP-competitive manner. It displays no significant inhibition of ZAPK, SYKK, PKCT, PKA and JAK3. Decreases food intake in mice and inhibits the effects of AICAR and metformin. IT has been shown to inhibit BMP type I receptors ALK2, ALK3 and ALK6.

Additional Information

Alternate Name/Synonyms BML-275
COA Documentation:
Molecular Structure
Package ID Refrigerated
CHEMACX X1561649-0
Chemical name (IUPAC) 6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE
Handling Protect from moisture.
HAZARD CLASS Not Applicable
INCHI InChI=1S/C24H25N5O/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20/h4-11,16-18H,1-3,12-15H2
INDICATION Stroke
Soluble Soluble in DMSO
MDL NUMBER MFCD08705402
Molecular Formula C24H25N5O
MP/BOILING POINT 244.93 °C
PACKING GROUP Not Applicable
Peptide sequence Not Applicable
2013 Price 75
Size/Unit 5mg
SMILES C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3
THERAPEUTIC AREA Neurological Disorders
UN #'S Not Applicable
USE A potent inhibitor of AMPK
Product Number D-1310
CAS # 866405-64-3
Chemical Name 6-[4-(2-Piperidin-1-yl)-ethoxy)- phenyl)]-3-pyridin-4-yl- pyrazolo[1,5-a]-pyrimidine
Chemical Formula C24H25N5O
Alternative Name Compound C, AMPK INHIBITOR
Appearance Yellow Solid
Handling Protect from moisture.
Molecular Weight 399.5
Purity 99%
RTECS Not Applicable
Solubility Soluble in DMSO
Storage Temp -20°C

Dorsomorphin | Compound C | CAS# 866405-64-3 | AMPK Inhibitor. Also inhibits BMP type I receptors ALK2, ALK3 and ALK6

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  • Dorsomorphin | Compound C | CAS# 866405-64-3 | AMPK Inhibitor. Also inhibits BMP type I receptors ALK2, ALK3 and ALK6