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Product Description
Enzastaurin (Enz) is a potent and selective inhibitor of PKCβ with antiproliferative activity (IC50 = ~6 nM). Enz suprpresses VEGF-induced angiogenesis in the rat corneal micropocket assay, decreases microvessel density, and prevents VEGF secretion from human tumor cell xenografts in nude mice. Prolonged courses of Enz increase chemotherapy or radiation tumor growth delay of glioma, breast, and small cell lung cancer xenografts.
Additional Information
| Product Number | E-2048 |
| CAS # | 170364-57-5 |
| Chemical Formula | C32H29N5O2 |
| Appearance | Solid |
| Molecular Weight | 515.61 |
| Purity | ≥99% |
| Solubility | DMSO |
| Storage Temp | Keep cool and dry. Store at -20°C |
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All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
