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Helenalin | CAS[6754-13-8] | Anti-inflammatory & Anti-Neoplastic Agent

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Helenalin

CAS: 6754-13-8 Formula: C15H18O4 MW: 262.3 Appearance: White to off-white Solid Purity: 97%
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H-1300 500 ug
$268.32
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Potent anti-inflammatory and anti-neoplastic agent. Induces a CD95 death receptor-independent apoptosis even when the mitochondria protecting proteins Bcl-xL or Bcl-2 are overexpressed. Also an inhibitor of NF-B.

Additional Information

Product # H-1300
CAS # 6754-13-8
Chemical Name (3AR,5R,5AR,8AR,9S,9AS)-9-HYDROXY-5,8A-DIMETHYL-1-METHYLIDENE-3A,4,5,5A,9,9A-HEXAHYDROAZULENO[6,7-B]FURAN-2,8-DIONE
Formula C15H18O4
MW 262.3
Appearance White to off-white Solid
Purity 97%
Solubility Soluble in DMSO (10 mg/ml) or 100% ethanol.
Boiling Point 473.0±45.0 °C at 760 mmHg
Storage Temp -20°C
Therapeutic Area Oncological Disorders
Use An inhibitor of the transcription factor NFκB is a potent antiinflammatory and antineoplastic agent

Additional Information

MDL Number MFCD01674580
ChemACX X1021671-0
InChI InChI=1S/C15H18O4/c1-7-6-10-12(8(2)14(18)19-10)13(17)15(3)9(7)4-5-11(15)16/h4-5,7,9-10,12-13,17H,2,6H2,1,3H3/t7-,9+,10-,12-,13+,15+/m1/s1
SMILES C[C@@H]1C[C@@H]2[C@H]([C@@H]([C@]3([C@H]1C=CC3=O)C)O)C(=C)C(=O)O2

Additional Information

GHS Pictograms
UN #'S UN 3462
PACKING GROUP II
Handling Store in Tightly Sealed Vial Warning.Toxic.

Additional Information

Certificate of Analysis 1 H-1300, E1403.pdf
Certificate of Analysis 2 H-1300_H-1300,_B1928.pdf
Certificate of Analysis 3 H-1300_H-1300,_B1144.pdf

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Helenalin

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