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Helenalin

HELENALIN
Product Number: H-1300

        

Details

Potent anti-inflammatory and anti-neoplastic agent. Induces a CD95 death receptor-independent apoptosis even when the mitochondria protecting proteins Bcl-xL or Bcl-2 are overexpressed. Also an inhibitor of NF-B

Additional Information

COA Documentation:
MP/BOILING POINT 473.0±45.0 °C at 760 mmHg
CHEMACX X1021671-0
Handling Store in Tightly Sealed Vial Warning.Toxic.
INDICATION Breast Cancer
MDL NUMBER MFCD01674580
PACKING GROUP II
INCHI InChI=1S/C15H18O4/c1-7-6-10-12(8(2)14(18)19-10)13(17)15(3)9(7)4-5-11(15)16/h4-5,7,9-10,12-13,17H,2,6H2,1,3H3/t7-,9+,10-,12-,13+,15+/m1/s1
SMILES C[C@@H]1C[C@@H]2[C@H]([C@@H]([C@]3([C@H]1C=CC3=O)C)O)C(=C)C(=O)O2
THERAPEUTIC AREA Oncological Disorders
UN #'S UN 3462
USE An inhibitor of the transcription factor NFκB is a potent antiinflammatory and antineoplastic agent
Product Number H-1300
CAS # 6754-13-8
Chemical Name (3AR,5R,5AR,8AR,9S,9AS)-9-HYDROXY-5,8A-DIMETHYL-1-METHYLIDENE-3A,4,5,5A,9,9A-HEXAHYDROAZULENO[6,7-B]FURAN-2,8-DIONE
Chemical Formula C15H18O4
Appearance White to off-white Solid
Handling Store in Tightly Sealed Vial Warning.Toxic.
Molecular Weight 262.3
Purity 97%
Solubility Soluble in DMSO (10 mg/ml) or 100% ethanol.
Storage Temp -20°C

Helenalin

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