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Multidrug Resistance(MDR) Inhibitors
Multidrug resistance(MDR) inhibitors are ATP binding cassette (ABC) multidrug resistance protein inhibitors. P-glycoprotein(P-gp, ABCB1, MDR1) is one of human ABC transporters which effluxes xenobiotics from cells resulting in MDR. Cancer cells frequently overexpress P-glycoproteins or multidrug transporters.