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Product Description
Beta-Lactamase, E.C.3.5.2.6, penicillin amido-beta-lactam hydrolase, isolated from the organism, Bacillus cereus 569/H9Beta Lactamase is used to destroy/remove Beta-Lactam antibiotics. Has broad sprectrum of activity against both penicillins (penicillinase or Beta I activity) and cephalosporins (cephalosporinase or Beta II activity). BETA-LACTAMASE will inactivate the following antibiotics: Beta-Lactam: Benzylpenicillin, ampicillin, amoxycillin, carbenicillin, methicillin, cloxacillin, flucloxacillin. Cephalosporins: cephaloridine, cephalothin, cephalexin, cephazolin, cephradine*,cefuroxime*, cefoxitin*, ceftizoxime*, cefpiramide* (*require longer incubations for total inactivation). Carbapenems: Bacillus cereus Beta-Lactamse II has been reported to hydrolyse some carbapenems. Sterilty: The vialed products are bacteriologically sterile. Sterilization is via gamma irradiation, with no detectable growth in Nutrient Broth at 37 °C for fourteen days. The product is vialed to contain: >500 Beta I units / vial and >50 Beta II units/ vial. A Beta I unit is defined as the amount of enzyme that will catalyse the hydrolysis of 1.0 micromole of benzylpenicillin per minute at 25°C and pH 7.0. Beta II unit is defined as the amount of enzyme that will catalyse the hydrolysis of 1.0 micromole of cephalosporin C per minute at 25°C and pH 7.0.
Additional Information
| Document Links | COA Documentation: |
| Product Number | L-1163 |
| CAS # | CAS [9073-60-3] |
| Chemical Name | penicillin amido-β-lactam hydrolase |
| Alternative Name | Beta-Lactamase |
| Appearance | Lyophilized Powder containing buffer and zinc salts |
| Preparation | Vialed products are stabled as supplied > 2yrs. |
| Purity | >500 Beta I Units and >50 Beta II Units |
| Solubility | Soluble in Water. |
| Storage Temp | +4°C |
Notice
All products sold by A.G. Scientific are strictly for Laboratory, Bioproduction or Manufacturing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
