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Etoposide

ETOPOSIDE
Product Number: E-2004

        

Details

Topoisomerase II inhibitor. Anti-tumor reagent. Widely used apoptosis inducer by FasL. Semisynthetically derived frompodophyllotoxin.

Additional Information

COA Documentation:
Molecular Structure
CHEMACX X1004425-4
Chemical name (IUPAC) 4-DESMETHYLEPIPODOPHYLLOTOXIN 9-(4,6-O-ETHYLIDENE)-BETA-D-GLUCOPYRANOSIDE
Handling TOXIC.Store in Tightly Sealed Vial Protect from Light Protect from Moisture. Possible Carcinogen. Store DMSO solutions short term 4C, long term at -20C.
HAZARD CLASS Not Applicable
INCHI InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1
INDICATION Kaposi Sarcoma,Ewing Sarcoma,Testicular Cancer
Soluble Soluble in DMSO, DMF, Ethyl ether,Chloroform:methanol (1:1). Slightly soluble in methanol or acetone;insoluble in water
MDL NUMBER MFCD00869325
Molecular Formula C29H32O13
MP/BOILING POINT 236-251 °C/798.1 °C at 760 mmHg
PACKING GROUP Not Applicable
Peptide sequence Not Applicable
2013 Price 82
Size/Unit 100mg
SMILES C[C@@H]1OC[C@@H]2[C@@H](O1)[C@@H]([C@H]([C@@H](O2)O[C@@H]3c4cc5c(cc4[C@H]([C@@H]6[C@@H]3COC6=O)c7cc(c(c(c7)OC)O)OC)OCO5)O)O
THERAPEUTIC AREA Oncological Disorders
UN #'S Not Applicable
USE Inhibits DNA synthesis via topoisomerase II inhibition used as a form of chemotherapy for cancers
Product Number E-2004
CAS # 33419-42-0
Chemical Name 4-Desmethylepipodophyllotoxin 9-(4,6-0-ethylidene)-β- D-glucopyranoside
Chemical Formula C29H32O13
Alternative Name VP-16-213
Appearance White to Off-White Solid
Handling TOXIC.Store in Tightly Sealed Vial Protect from Light Protect from Moisture. Possible Carcinogen. Store DMSO solutions short term 4C, long term at -20C.
Molecular Weight 588.6
Purity 97%
RTECS KC0190000
Solubility Soluble in DMSO, DMF, ethyl ether or chloroform:methanol (1:1)
Storage Temp Room Temp

Etoposide

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  • Etoposide | CAS 33419-42-0 | Topoisomerase II inhibitor | Anti-tumor