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Product Description
6BIO is a cell-permeable, highly potent, selective, reversible, and ATP-competitive inhibitor of GSK-3α/β (IC50 = 5 nM).
Inhibition of GSK by 6BIO has been shown to result in the activation of the Wnt signaling pathway and sustained pluripotency of human and murine embryonic stem cells (ESCs).
Additional Information
| Product Number | G-1247 |
| CAS # | CAS [667463-62-9] |
| Chemical Name | (2′Z,3′E)-6-Bromoindirubin-3′-oxime |
| Chemical Formula | C16H10BrN3O2 |
| Alternative Name | 6BIO , GSK-3 Inhibitor | CAS [667463-62-9] | A.G. Scientific |
| Appearance | Dark Red to Purple solid. |
| Molecular Weight | M.W.356.2 |
| Preparation | Packaged under inert gas. |
| Purity | Purity:≥98% |
| Solubility | DMSO |
| Storage Temp | -20º C |
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