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Product Description
Reduces LPS-induced tyrosine phosphorylation of p42MAPK in murine peritoneal macrophages at 50 µM. At 100μM does not inhibit EGFR, Her-2/neu receptor or PDGF-R. Studies indicate AG-126 prevents lipopolysaccharide-induced lethal toxicity in mice. Inhibitor of tyrosine kinase-dependent B cell receptor signaling.
Additional Information
| Product Number | A-1208 |
| CAS # | CAS [118409-62-4] |
| Chemical Name | (3-Hydroxy-4-nitrobenzylidene)malononitrilellα-Cyano-(3-hydroxy-4-nitro)cinnamonitrile |
| Chemical Formula | C10H5N3O3 |
| Alternative Name | Tyrphostin AG 126, Tyrphostin A10 |
| Appearance | Yellow Solid |
| Molecular Weight | M.W. 215.2 |
| Purity | Purity: ≥98% |
| Solubility | Soluble in DMSO (25mg/ml) or 100% ethanol. |
| Storage Temp | -20°C |
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All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
