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Hedgehog Signaling

The Hedgehog (Hh) family of secreted signaling proteins plays a crucial role in development of diverse animal phyla, from Drosophila to humans, regulating morphogenesis of a variety of tissues and organs. Hh signaling is also involved in control of stem cell proliferation in adult tissues and aberrant activation of the Hh pathway has been linked to multiple types of human cancer. Members of the Hh family bind to patched (ptc), thus releasing smoothened (smo) to transduce a signal. Transcriptional activation occurs through the GLI family of proteins resulting in activation of target genes.

 

Click here to View the Hedgehog Signaling Pathway

 

 

  1. CRT Inhibitor, iCRT5

    CRT Inhibitor, iCRT5

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-2273 18623-44-4 5 mg
    $87.89
    25 mg
    $330.88
  2. Cyclopamine

    Cyclopamine

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    C-1405 4449-51-8 1 mg
    $41.36
    5 mg
    $93.06
  3. DiscoveryPak Hedgehog (Hh) Signaling Pathway Inhibitors Set

    DiscoveryPak Hedgehog (Hh) Signaling Pathway Inhibitors Set

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    D-2291 6 inhibitors
    $506.87
  4. GANT58

    GANT58

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    G-2333 64048-12-0 5 mg
    $93.91
    25 mg
    $373.48
  5. GANT61

    GANT61

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    G-1233 500579-04-4 1 mg
    $202.75
  6. GDC-0449

    GDC-0449

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    G-2334 879085-55-9 5 mg
    $133.39
    25 mg
    $528.21
  7. Hh Signaling Pathway Antagonist

    Hh Signaling Pathway Antagonist

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    H-2354 330796-24-2 1 mg
    $112.04
  8. JK 184

    JK 184

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    J-2367 315703-52-7 1 mg
    $104.58
  9. Purmorphamine

    Purmorphamine

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    P-1633 483367-10-8 1 mg
    $42.68
    5 mg
    $154.73
  10. Robotnikinin | Sonic HedgeHog inhibitor | Embryogenesis inhibitor

    Robotnikinin ,Shh inhibitor

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    R-2028 1 mg
    $293.45
    5x1 mg
    $1,186.80
  11. SANT-1

    SANT-1

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    S-2162 304909-07-7 1 mg
    $82.72
    5 mg
    $263.67
  12. SANT-2

    SANT-2

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    S-2424 329196-48-7 1 mg
    $58.69
    5 mg
    $176.07
  13. Tomatidine hydrochloride

    Tomatidine hydrochloride

    PRODUCT # CAS # SIZE PRICE QUANTITY BUY NOW
    T-2465 6192-62-7 25 mg
    $80.03