![Necrostatin-1, Nec-1 Structure| CAS[4311-88-0]| Necroptosis Inhibitor, non-apoptotic cell death pathway. Critical role of RIP1 Kinase in necroptosis.| A.G.Scientific](http://www.agscientific.com/media/catalog/product/cache/1/thumbnail/56x/5e06319eda06f020e43594a9c230972d/placeholder/default/iso9001_4.gif "Necrostatin-1, Nec-1 Structure| CAS[4311-88-0]| Necroptosis Inhibitor, non-apoptotic cell death pathway. Critical role of RIP1 Kinase in necroptosis.| A.G.Scientific")
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Product Description
Inhibits necroptosis, a non-apoptotic cell death pathway. Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. Inhibits RIP1 kinase, the key upstream kinase involved in the activation of necroptosis (EC₅₀ = 180 nM)
Additional Information
COA Documentation: |
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| Product Number | N-1227 |
| CAS # | 4311-88-0 |
| Chemical Name | Methythiohydantoin-DL-tryptophan |
| Chemical Formula | C13H13N3OS |
| Alternative Name | Nec-1 |
| Appearance | Yellow solid |
| Purity | ≥98 (TLC) |
| Solubility | Soluble in DMSO (25mg/ml) or 100% ethanol(6mg/ml) |
| Storage Temp | -20°C |
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![Necrostatin-1, Nec-1 Structure| CAS[4311-88-0]| Necroptosis Inhibitor, non-apoptotic cell death pathway. Critical role of RIP1 Kinase in necroptosis.| A.G.Scientific](http://www.agscientific.com/media/catalog/product/cache/1/image/5e06319eda06f020e43594a9c230972d/placeholder/default/iso9001_lg_1.gif "Necrostatin-1, Nec-1 Structure| CAS[4311-88-0]| Necroptosis Inhibitor, non-apoptotic cell death pathway. Critical role of RIP1 Kinase in necroptosis.| A.G.Scientific")
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