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A synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs. Pam3CSK4 is a potent activator of the proinflammatory transcription factor NF-kB. Activation is mediated by the interaction between Toll-like receptor 1 (TLR1) and Toll-like receptor 2 (TLR2).
|Chemical Name||Pam3CSK4 . 3HCl|
|Chemical Formula||C81H156N10O13S. 3HCl|
|Purity||Confirmed by ESI-MS|
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