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Product Description
A potent and selective FGFR1 tyrosine kinase inhibitor (IC50 = 21.5 nM). Blocking of the FGFR signaling pathway by PD 173074 leads to self-renewal of stem cells via ERK1/2 activation. Treatment of FGF2-expressing human multipotent adipose-derived stem cells with PD173074 decreases dramatically their clonogenicity and differentiation potential.
Additional Information
| Product Number | P-2390 |
| CAS # | 219580-11-7 |
| Chemical Name | N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N’-(1,1-dimethylethyl)urea |
| Chemical Formula | C28H41N7O3 |
| Appearance | Crystalline solid |
| Molecular Weight | 523.67 |
| Purity | ≥98% by TLC |
| Solubility | DMSO (10 mg/ml) |
| Storage Temp | -20°C |
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All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
