Astringenin; (E)-4-[2-(3,5Dihydroxyphenyl)ethenyl]1,2- benzenediol; 3,3′,4,5′-Tetrahydroxy-trans-stilbene
10083-24-6
244.3
C14H12O4
DMSO, Ethanol, Methanol, Acetone, Ethyl acetate, Water
2-8°C
Piceatannol is a selective protein tyrosine kinase Syk inhibitor (IC50~10 M). In RBL-2H3 cells the selective inhibition of Syk by piceatannol results in inhibition of Fc R1-mediated signaling.
Picetannol also works as an activator of human deacetylase SIRT1. A natural stilbene and an analogue of Resveratrol. Piceatannol exhibits potential anticancer properties as shown by its ability to suppress proliferation of a wide variety of tumor cells, including leukemia, lymphoma, cancers of the breast, prostate, colon, and melanoma.
Also inhibits JAK-1 and Syk kinase; blocks adipogenesis of 3T3-L1 preadipocytes in a dose-dependent manner. Originally isolated from Euphorbia lagascae.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
