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Purmorphamine

PURMORPHAMINE
Product Number: P-1633

        

Details

A cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells (EC₅₀ = 1 µM) and in MC3T3-E1 lineage-committed preosteoblasts. Also shown to induce transdifferentiation in pre-adipocytes and myoblasts. Its effects are reported to be synergistic with bone morphogenetic protein-4 (BMP-4). Reported to induce osteogenesis by activation of the Hedgehog signaling pathway.

Additional Information

Product Number P-1633
Chemical Name 2-(1-Naphthoxy)-6-(4-morpholinoanilino)-9-cyclohexylpurine
Chemical Formula C31H32N6O2
Alternative Name Shh Signaling Agonist
Appearance Beige solid. Packaged under inert gas.
Handling Protect from light. Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Molecular Weight M.W.520.6
Purity Purity:≥98% by HPLC
Solubility DMSO (200 mg/ml)
Storage Temp +4ºC

Purmorphamine