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Neurofibromin is a tumor suppressor with GTPase activity that modulates the ras pathway. Defects in or deficiency of this protein can lead to Neurofibromatosis disease which can result in tumor formation and abnormalities of multiple tissues derived from the embryonic neural crest.
|Chemical Name||Species cross-reactivity: Mam, Applications/dilutions: ICC/IF (1/100 – 1/500), WB (1/250 – 1/1,000)|
|Appearance||0.2 ml with 50% glycerol and 0.01% sodium azide.|
|Solubility||SOURCE: Rabbits were immunized with a synthetic peptide corresponding to amino acid residues 216-226 of rat and mouse GAP-43. n-(C)KE DPE ADQ EHA-c|
|Storage Temp||-20º C|
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