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Rapamycin | CAS [53123-88-9] | Immunosuppressive Macrolide Antibiotic

Rapamycin | CAS [53123-88-9] | Immunosuppressive Macrolide Antibiotic

COA Documentation: R-1018_R-1018,_A9560A,_r01.pdf R-1018_R-1018,_C1065.pdf Rapamycin \| CAS [53123-88-9] \| Immunosuppressive Macrolide Antibiotic Product Number: R-1018
Price	Price	Qty	Add to Cart
1x1 mg	$22.00
1x5 mg	$62.00
1x25 mg	$202.00

Product Description

Rapamycin is a triene macrolide antibiotic which demonstrates immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as, the activation of p70 S6 kinase.

Rapamycin is also an anti-inflammatory agent.

Attached are a few published references from researchers who have used our Rapamycin product. We respectfully thank them for their trust in our product. Inquire for a full reference list.

http://cancerres.aacrjournals.org/content/67/8/3794.full.pdf+html

http://hmg.oxfordjournals.org/content/19/10/1908.full.pdf+html

http://www.jneurosci.org/content/31/5/1693.full.pdf+html

http://vir.sgmjournals.org/content/90/12/3002.full.pdf+html

http://jvi.asm.org/content/84/15/7683.full.pdf+html

http://cardiovascres.oxfordjournals.org/content/68/2/204.full.pdf+html

Seeking published researchers utilizing our Rapamycin product? Hit the hot link for the full paper.

1. Identification of Autophagosome-associated Proteins and Regulators by Quantitative Proteomic Analysis and Genetic Screens, Jörn Dengjel, Maria Høyer-Hansen, et al,Mar 2012; 11: M111.014035.

2. Rapamycin-mediated mTOR inhibition attenuates survivin and sensitizes glioblastoma cells to radiation therapy, Arunkumar Anandharaj, Senthilkumar Cinghu, et al,Apr 2011; 43: 292 - 300.

3. BIOSYNTHESIS AND BIODEGRADATION:
Proteasomal degradation of Sfp1 contributes to the repression of ribosome biogenesis during starvation and is mediated by the proteasome activator Blm10, Antonio Diaz Lopez, Krisztina Tar, et al, Mar 2011; 22: 528 - 540.

4. Avian Reovirus Nonstructural Protein p17-Induced G₂/M Cell Cycle Arrest and Host Cellular Protein Translation Shutoff Involve Activation of p53-Dependent Pathways, Julius L. C. Chulu, Wei R. Huang, et al, Aug 2010; 84: 7683 - 7694.

5. **pathogenesis and potential therapies in Tsc2^+/– mice,** Jiumei Cao, Limin Gong, et al, May 2010; 19: 1908 - 1920.

6. Therapeutic Effect of Rapamycin on Gallbladder Cancer in a Transgenic Mouse Model, Qi Wu, Kaoru Kiguchi, et al, Apr 2007; 67: 3794 - 3800.

Additional Information

COA Documentation: R-1018_R-1018,_A9560A,_r01.pdf R-1018_R-1018,_C1065.pdf
Product Number	R-1018
CAS #	CAS [53123-88-9]
Chemical Name	Isolated from Streptomyces hygroscopicus
Chemical Formula	C₅₁H₇₉NO₁₃
Alternative Name	RAPA, Rapamune, Sirolimus, AY-22989, NSC-226080
Appearance	White to Off White Solid
Melting Point	MP: 183-185°C
Merck Index	Merck Index: 13.8202.2001
Molecular Weight	M.W. 914.2
Purity	Purity: >98%
Solubility	Soluble in DMSO and Methanol.
Storage Temp	-20°C

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Rapamycin | CAS [53123-88-9] | Immunosuppressive Macrolide Antibiotic

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Rapamycin | CAS [53123-88-9] | Immunosuppressive Macrolide Antibiotic

COA Documentation:

Product Description

Attached are a few published references from researchers who have used our Rapamycin product. We respectfully thank them for their trust in our product. Inquire for a full reference list.

http://cancerres.aacrjournals.org/content/67/8/3794.full.pdf+html

http://hmg.oxfordjournals.org/content/19/10/1908.full.pdf+html

http://www.jneurosci.org/content/31/5/1693.full.pdf+html

http://vir.sgmjournals.org/content/90/12/3002.full.pdf+html

http://jvi.asm.org/content/84/15/7683.full.pdf+html

http://cardiovascres.oxfordjournals.org/content/68/2/204.full.pdf+html

Seeking published researchers utilizing our Rapamycin product? Hit the hot link for the full paper.

1. Identification of Autophagosome-associated Proteins and Regulators by Quantitative Proteomic Analysis and Genetic Screens, Jörn Dengjel, Maria Høyer-Hansen, et al,Mar 2012; 11: M111.014035.

2. Rapamycin-mediated mTOR inhibition attenuates survivin and sensitizes glioblastoma cells to radiation therapy, Arunkumar Anandharaj, Senthilkumar Cinghu, et al,Apr 2011; 43: 292 - 300.

3. BIOSYNTHESIS AND BIODEGRADATION:
Proteasomal degradation of Sfp1 contributes to the repression of ribosome biogenesis during starvation and is mediated by the proteasome activator Blm10, Antonio Diaz Lopez, Krisztina Tar, et al, Mar 2011; 22: 528 - 540.

4. Avian Reovirus Nonstructural Protein p17-Induced G₂/M Cell Cycle Arrest and Host Cellular Protein Translation Shutoff Involve Activation of p53-Dependent Pathways, Julius L. C. Chulu, Wei R. Huang, et al, Aug 2010; 84: 7683 - 7694.

5. **pathogenesis and potential therapies in Tsc2^+/– mice,** Jiumei Cao, Limin Gong, et al, May 2010; 19: 1908 - 1920.

6. Therapeutic Effect of Rapamycin on Gallbladder Cancer in a Transgenic Mouse Model, Qi Wu, Kaoru Kiguchi, et al, Apr 2007; 67: 3794 - 3800.

Additional Information

COA Documentation:

Notice

STILL COMPARING & NOT READY TO BUY? CLICK HERE FOR 10 % OFF YOUR NEXT PURCHASE.

Require bulk price at a PREFERRED DISCOUNT$$$? CLICK HERE.

Follow our latest scientific offerings WITH OUR DAILY BLOG. CLICK HERE.

All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.

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Call Us Toll Free: 1-877-452-9925 (US & Canada Only)

Category Navigation:

You're currently on:

Rapamycin | CAS [53123-88-9] | Immunosuppressive Macrolide Antibiotic

COA Documentation:

Product Description

Attached are a few published references from researchers who have used our Rapamycin product. We respectfully thank them for their trust in our product. Inquire for a full reference list.

http://cancerres.aacrjournals.org/content/67/8/3794.full.pdf+html

http://hmg.oxfordjournals.org/content/19/10/1908.full.pdf+html

http://www.jneurosci.org/content/31/5/1693.full.pdf+html

http://vir.sgmjournals.org/content/90/12/3002.full.pdf+html

http://jvi.asm.org/content/84/15/7683.full.pdf+html

http://cardiovascres.oxfordjournals.org/content/68/2/204.full.pdf+html

Seeking published researchers utilizing our Rapamycin product? Hit the hot link for the full paper.

1. Identification of Autophagosome-associated Proteins and Regulators by Quantitative Proteomic Analysis and Genetic Screens, Jörn Dengjel, Maria Høyer-Hansen, et al,Mar 2012; 11: M111.014035.

2. Rapamycin-mediated mTOR inhibition attenuates survivin and sensitizes glioblastoma cells to radiation therapy, Arunkumar Anandharaj, Senthilkumar Cinghu, et al,Apr 2011; 43: 292 - 300.

3. BIOSYNTHESIS AND BIODEGRADATION: Proteasomal degradation of Sfp1 contributes to the repression of ribosome biogenesis during starvation and is mediated by the proteasome activator Blm10, Antonio Diaz Lopez, Krisztina Tar, et al, Mar 2011; 22: 528 - 540.

4. Avian Reovirus Nonstructural Protein p17-Induced G2/M Cell Cycle Arrest and Host Cellular Protein Translation Shutoff Involve Activation of p53-Dependent Pathways, Julius L. C. Chulu, Wei R. Huang, et al, Aug 2010; 84: 7683 - 7694.

5. pathogenesis and potential therapies in Tsc2+/– mice, Jiumei Cao, Limin Gong, et al, May 2010; 19: 1908 - 1920.

6. Therapeutic Effect of Rapamycin on Gallbladder Cancer in a Transgenic Mouse Model, Qi Wu, Kaoru Kiguchi, et al, Apr 2007; 67: 3794 - 3800.

Additional Information

COA Documentation:

Notice

Require bulk price at a PREFERRED DISCOUNT$$$? CLICK HERE.

Follow our latest scientific offerings WITH OUR DAILY BLOG. CLICK HERE.

All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.

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3. BIOSYNTHESIS AND BIODEGRADATION:
Proteasomal degradation of Sfp1 contributes to the repression of ribosome biogenesis during starvation and is mediated by the proteasome activator Blm10, Antonio Diaz Lopez, Krisztina Tar, et al, Mar 2011; 22: 528 - 540.

4. Avian Reovirus Nonstructural Protein p17-Induced G₂/M Cell Cycle Arrest and Host Cellular Protein Translation Shutoff Involve Activation of p53-Dependent Pathways, Julius L. C. Chulu, Wei R. Huang, et al, Aug 2010; 84: 7683 - 7694.

5. **pathogenesis and potential therapies in Tsc2^+/– mice,** Jiumei Cao, Limin Gong, et al, May 2010; 19: 1908 - 1920.