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Fermentation Production

A.G. Scientific is a world leader in the production of antibiotics that are produced by a novel process of fermentation.  A.G. has enjoyed particular success in large-scale production, extraction and purification into crytalline product. The most popular of the fermentation products are:

Hygromycin B is a standard antibiotic that selects for exclusively hygromycin resistant cells. 

Puromycin is an antibiotic that inhibits translation via premature chain termination; it is toxic to both prokaryotic and eukaryotic cells. 

Anisomycin Anti-fungal antibiotic which inhibits Protein Synthesis.

G418 inhibits polypeptide synthesis in prokaryotic and eukaryotic cells and is structurally related to gentamycin

A.G. Scientific delivers quality assured reagents directly to scientists, from small-scale to bulk orders. Our leadership in bulk supply allows us to provide custom product packaging and create multiple product forms. We offer “just in time” delivery, private labeling, and custom formulations for specific research needs.
 

 

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(+)-Aphidicolin, Nigrospora oryzae
Product Number: A-1026

Product Name Price Qty
(+)-Aphidicolin, Nigrospora oryzae - 1x1 mg
$55.00
(+)-Aphidicolin, Nigrospora oryzae - 1x5 mg
$185.00
(+)-Aphidicolin, Nigrospora oryzae - 1x25 mg
$670.00
Reversible Inhibitor of eukaryotic nuclear DNA replication. Learn More

17-AAG
Product Number: A-1256

Product Name Price Qty
17-AAG - 1x500 μg
$50.00
17-AAG - 1x1 mg
$70.00
17-AAG - 1x5mg
$185.00
17-AAG is an ansamycin antibiotic which acts as an anti-tumor agent. Specifically, 17-AAG binds and inhibits Hsp90 (Heat shock protein 90). Learn More

17DMAG
Product Number: A-1298

Product Name Price Qty
17DMAG - 1x1mg
$70.00
17DMAG - 1x5 mg
$185.00
A semi-synthetic derivate of Geldanamcyin, 17-DMAG binds to Hsp90 and alters its function. A water soluble & cell-permeable analog of Gelda Learn More

4-Bromo-A23187
Product Number: A-1130

Product Name Price Qty
4-Bromo-A23187 - 1x1 mg
$80.00
4-Bromo-A23187 - 1x5 mg
$240.00
Nonfluorescent calcium ionophore used as a calibration standard for determining cytoplasmic calcium ions by fluorescent probes. Learn More

7-Amino-Actinomycin D
Product Number: A-1132

Product Name Price Qty
7-Amino-Actinomycin D - 1x1 mg
$70.00
7-Amino-Actinomycin D - 1x5 mg
$240.00
Fluorescent DNA Stain. Binds Single stranded DNA. Useful tool in determining apoptosis. Learn More

A23187, Free Acid
Product Number: A-1020

Product Name Price Qty
A23187, Free Acid - 1x5 mg
$50.00
A23187, Free Acid - 1x10 mg
$75.00
A23187, Free Acid - 1x50 mg
$320.00
A widely used ionophore. It has the ability to increase the intracellular concentrations of cations and is widely used to increase the intra Learn More

A23187, Mixed Calcium-Magnesium Salt
Product Number: A-1128

Product Name Price Qty
A23187, Mixed Calcium-Magnesium Salt - 1x5 mg
$52.50
A23187, Mixed Calcium-Magnesium Salt - 1x10 mg
$84.00
Used in cell activation experiments when calcium dose-response data are not required. Molar ratio Ca:Mg~1:1. Learn More

Actinomycin D, Streptomyces sp.
Product Number: A-1022

Product Name Price Qty
Actinomycin D, Streptomyces sp. - 1x5 mg
$45.00
Actinomycin D, Streptomyces sp. - 1x10 mg
$70.00
Actinomycin D, Streptomyces sp. - 1x25 mg
$155.00
Actinomycin D, Streptomyces sp. - 1x100 mg
$455.00
An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymera Learn More

Actinopyrone A, Streptomyces pactum
Product Number: A-1290

Product Name Price Qty
Actinopyrone A, Streptomyces pactum - 1x0.50 mg
$215.00
Actinopyrone A, Streptomyces pactum - 1x2.50 mg
$730.00
Actinopyrone A is a -pyrone compound isolated from a Streptomyces sp.. It has selective (>106 fold) andpotent (MIC 0.0001 g/ml) activity Learn More

Alamethicin
Product Number: A-1286

Product Name Price Qty
Alamethicin - 1x5 mg
$89.00
Alamethicin - 1x10 mg
$155.00
Alamethicin - 1x50 mg
$610.00
Membrane permeabilizing Antibiotic. Increases [32P] incorporation into phosphatidylinositol-4-phosphate. Learn More

Anisomycin, Streptomyces griseolus
Product Number: A-1049

Product Name Price Qty
Anisomycin, Streptomyces griseolus - 1x100 mg
$160.00
Anisomycin, Streptomyces griseolus - 1x500 mg
$595.00
Anti-fungal antibiotic which inhibits Protein Synthesis. Also activates p54, MAP Kinases and Stress-Activated Protein Kinases. Used in Marti Learn More

Ascomycin, Streptomyces hygroscopicus var ascomyceticus
Product Number: A-1258

Product Name Price Qty
Ascomycin, Streptomyces hygroscopicus var ascomyceticus - 1x1 mg
$92.00
Ascomycin, Streptomyces hygroscopicus var ascomyceticus - 1x5 mg
$378.00
An ethyl analog of FK506 with strong immunosuppressant properties. Acts by binding to immunophilins, especially macrophilin-12. It appears t Learn More

Bafilomycin A1 from Streptomyces griseus
Product Number: B-1183

Product Name Price Qty
Bafilomycin A1 from Streptomyces griseus - 1x1 mg
$165.00
A macrolide antibiotic that acts as a specific inhibitor of vacuolar-type H+-ATPase. Useful in distinguishing among different types of ATPas Learn More

Bafilomycin B1 from Streptomyces griseus
Product Number: B-1185

Product Name Price Qty
Bafilomycin B1 from Streptomyces griseus - 1x1 mg
$70.00
A macrolide antibiotic that acts as a specific inhibitor of vacuolar-type H+-ATPase. Learn More

Bafilomycin B2
Product Number: B-1245

Product Name Price Qty
Bafilomycin B2 - 1x50 mg
$0.00
from Streptomyces griseus. Inquire for availability. Learn More

Borrelidin, Streptomyces sp.
Product Number: B-1260

Product Name Price Qty
Borrelidin, Streptomyces sp. - 1x1mg
$237.00
Borrelidin, an 18-membered macrolide-polyketide, is a compound with anti-viral, anti-bacterial, anti-malarial, and anti-angiogenic propertie Learn More

Brefeldin A, Eupenicillium brefeldianum
Product Number: B-1009

Product Name Price Qty
Brefeldin A, Eupenicillium brefeldianum - 1x10 mg
$120.00
Brefeldin A, Eupenicillium brefeldianum - 1x25 mg
$260.00
Brefeldin A, Eupenicillium brefeldianum - 1x100 mg
$735.00
Inhibitor of protein translocation from endoplasmic reticulum (ER) to the Golgi apparatus. Learn More

Cerulenin
Product Number: C-1375

Product Name Price Qty
Cerulenin - 1x5 mg
$60.00
Cerulenin - 1x10 mg
$105.00
Cerulenin - 1x50 mg
$415.00
Fatty acid synthase (FAS) inhibitor reported to bind in equimolar ratio to b-keto-acyl-ACP synthase, thus inhibiting protein acylation. Learn More

Chelerythrine Chloride
Product Number: C-1021

Product Name Price Qty
Chelerythrine Chloride - 1x5 mg
$72.00
Chelerythrine Chloride - 1x25mg
$295.00
Potent and selective inhibitor of Protein Kinase C. Learn More

Chlorothricin, Streptomyces sp.
Product Number: C-1400

Product Name Price Qty
Chlorothricin, Streptomyces sp. - 1x1 mg
$110.00
Chlorothricin, Streptomyces sp. - 1x5 mg
$375.00
The tetronic acid, chlorothricin is an unusual macrocyclic antibiotic from Streptomyces sp. Related to kijanimicin, sccharocarcins, tetrocar Learn More

Chromomycin A3 Streptomyces Griseus
Product Number: C-1023

Product Name Price Qty
Chromomycin A3 Streptomyces Griseus - 1x5 mg
$105.00
Chromomycin A3 Streptomyces Griseus - 1x10 mg
$185.00
Antibiotic produced by Streptomyces grieus that inhibits RNA synthesis. Also used as a fluorescent dye to determine DNA concentrations. Othe Learn More

Chrysomycin A, Streptomyces sp.
Product Number: C-1410

Product Name Price Qty
Chrysomycin A, Streptomyces sp. - 1x0.50 mg
$215.00
Chrysomycin A, Streptomyces sp. - 1x2.50 mg
$730.00
Chrysomycin A is the major analogue in a complex of C-glycoside antitumor actives isolated fromStreptomyces. Chrysomycin A, with a vinyl g Learn More

Chrysomycin B, Streptomyces sp.
Product Number: A-1412

Product Name Price Qty
Chrysomycin B, Streptomyces sp. - 1x0.50 mg
$215.00
Chrysomycin B, Streptomyces sp. - 1x2.50 mg
$730.00
Chrysomycin B is a minor analogue in a complex of C-glycoside antitumor actives isolated fromStreptomyces. Chrysomycin B, containing a met Learn More

Citrinin, Penicillium citrinum
Product Number: C-1109

Product Name Price Qty
Citrinin, Penicillium citrinum - 1x5 mg
$60.00
Citrinin, Penicillium citrinum - 1x10 mg
$105.00
Mycotoxin which induces mitochondrial permeability transition. Also inhibits microtubule polymerization. Learn More

Cochliodinol, from Chaetomium globosum.
Product Number: C-1449

Product Name Price Qty
Cochliodinol, from Chaetomium globosum. - 1x500 ug
$150.00
Antibiotic, displaying antibacterial and anti-tumor activity. Learn More

Cochlioquinone A, Bipolaris leersia
Product Number: C-1401

Product Name Price Qty
Cochlioquinone A, Bipolaris leersia - 1x0.50 mg
$180.00
Cochlioquinone A, Bipolaris leersia - 1x2.50 mg
$615.00
Cochlioquinone A is the major component of a bioactive pigment isolated from Bipolaris leersia. It has beenfound to be an antagonist of th Learn More

Cochlioquinone B, Bipolaris leersia
Product Number: C-1403

Product Name Price Qty
Cochlioquinone B, Bipolaris leersia - 1x0.50 mg
$180.00
Cochlioquinone B, Bipolaris leersia - 1x2.50 mg
$615.00
Cochlioquinone B, the minor component of a bioactive pigment isolated from Bipolaris leersia, is an NADHubiquinonereductase inhibitor and Learn More

Concanamycin A, Streptomyces sp.
Product Number: C-1057

Product Name Price Qty
Concanamycin A, Streptomyces sp. - 1x100 μg
$175.00
Concanamycin A, Streptomyces sp. - 1x1 mg
$745.00
Antibiotic which is a specific inhibitor of vacuolar H+ ATPase. Learn More

Cycloheximide, Streptomyces griseus
Product Number: C-1189

Product Name Price Qty
Cycloheximide, Streptomyces griseus - 1x1 g
$30.00
Cycloheximide, Streptomyces griseus - 1x5 g
$75.00
Cycloheximide, Streptomyces griseus - 1x25 g
$295.00
An antibiotic produced by Streptomyces griseus, which acts as an inhibitor of protein synthesis in eukaryotes but not prokaryotes. In molecu Learn More

Cyclopiazonic acid, Penicillium cyclopium
Product Number: C-1025

Product Name Price Qty
Cyclopiazonic acid, Penicillium cyclopium - 1x10 mg
$75.00
Cyclopiazonic acid, Penicillium cyclopium - 1x50 mg
$297.00
Reversible inhibitor of endoplasmic reticulum Ca2+ ATPase. Does not increase IP3 levels. Learn More

Cyclosporin A, Fusarium solani
Product Number: C-1199

Product Name Price Qty
Cyclosporin A, Fusarium solani - 1x100 mg
$49.00
Cyclosporin A, Fusarium solani - 1x500 mg
$199.00
Potent immunosuppressor. Inhibitor of the mitochondrial permeability transition pore (MPTP) preventing necrosis in several models. Isolated Learn More

Cytochalasin A
Product Number: C-1111

Product Name Price Qty
Cytochalasin A - 1x5 mg
$165.00
Cytochalasin A - 1x10 mg
$285.00
A fungal metabolite that acts as an inhibitor of glucose transport and actin polymerization. Learn More

Cytochalasin B, Helminthosporium dematioideum
Product Number: C-1027

Product Name Price Qty
Cytochalasin B, Helminthosporium dematioideum - 1x5 mg
$87.00
Cytochalasin B, Helminthosporium dematioideum - 1x25 mg
$370.00
A fungal metabolite that acts as a microtubule inhibitor. Also induces cellular DNA Fragmentation. Learn More

Cytochalasin C
Product Number: C-1200

Product Name Price Qty
Cytochalasin C - 1x1 mg
$70.00
Cytochalasin C - 1x5 mg
$280.00
A fungal metabolite that acts as a potent inhibitor of actin filament and contractile microfilaments. Learn More

Cytochalasin D, Zygusporium mansonii
Product Number: C-1070

Product Name Price Qty
Cytochalasin D, Zygusporium mansonii - 1x1 mg
$65.00
Cytochalasin D, Zygusporium mansonii - 1x5 mg
$258.00
A fungal metabolite that acts as a potent inhibitor of actin filament and contractile microfilaments. Also shown to protect Hippocampal neur Learn More

Cytochalasin E, Aspergillus clavatus
Product Number: C-1197

Product Name Price Qty
Cytochalasin E, Aspergillus clavatus - 1x1 mg
$38.00
Cytochalasin E, Aspergillus clavatus - 1x5 mg
$150.00
Cytochalasin E, Aspergillus clavatus - 1x10 mg
$275.00
A fungal metabolite that inhibits angiogenesis & tumor growth. Enhances PKC-dependent process of secretion. Does not inhibit glucose transpo Learn More

Equisetin, Fusarium equiseti
Product Number: E-2028

Product Name Price Qty
Equisetin, Fusarium equiseti - 1x1 mg
$110.00
Equisetin, Fusarium equiseti - 1x5 mg
$375.00
The tetramic acid, Equisetin, is produced by a number of species of Fusarium. Interest in equisetin emergedwith reports of its inhibitory Learn More

Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-g-butyryl]-, Dihydrochloride
Product Number: F-1026

Product Name Price Qty
Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-g-butyryl]-, Dihydrochloride - 1x10 mg
$80.00
Forskolin, 7-Deacetyl-7-[O-(N-methylpiperazino)-g-butyryl]-, Dihydrochloride - 1x25 mg
$180.00
A vasodilator and hypotensive agent. Activates adenylate cyclase leading to an increase in the intracellular concentration of cAMP. Learn More

Fostriecin, Streptomyces Pulveraceous subsp. Fostreus
Product Number: F-1038

Product Name Price Qty
Fostriecin, Streptomyces Pulveraceous subsp. Fostreus - 1x10 μg
$150.00
Anti-tumor antibiotic. Catalytic inhibitor of topoisomerase II. Strong inhibitor of protein phosphatase 2A, weak inhibitor of PP-1. Learn More

Fumagillin, Aspergillus fumigatus
Product Number: F-1028

Product Name Price Qty
Fumagillin, Aspergillus fumigatus - 1x1 mg
$75.00
Fumagillin, Aspergillus fumigatus - 1x5 mg
$250.00
Fumagillin, Aspergillus fumigatus - 1x10 mg
$450.00
Fumagillin is an inhibitor of endothelial cell proliferation and angiogenesis. Fumagillin is also being investigated as potential treatment Learn More

Fumonisin B1, Fusarium moniliforme
Product Number: F-1022

Product Name Price Qty
Fumonisin B1, Fusarium moniliforme - 1x1 mg
$74.00
Fumonisin B1, Fusarium moniliforme - 1x5 mg
$295.00
Fungal metabolite, which inhibits spingomyelin biosynthesis in neuronal cells. Learn More

Fumonisin B2, Fusarium moniliforme
Product Number: F-1024

Product Name Price Qty
Fumonisin B2, Fusarium moniliforme - 1x1 mg
$155.00
Fumonisin B2, Fusarium moniliforme - 1x5 mg
$625.00
Fungal metabolite with structure similar to Fumonisin B1, induces cancer. Learn More

Geldanamycin, Streptomyces hygroscopicus
Product Number: G-1047

Product Name Price Qty
Geldanamycin, Streptomyces hygroscopicus - 1x500 μg
$40.00
Geldanamycin, Streptomyces hygroscopicus - 1x1mg
$65.00
Geldanamycin, Streptomyces hygroscopicus - 1x5 mg
$190.00
Geldanamycin is a benzoquinone ansamycin antibiotic which binds to Hsp90 (Heat Shock Protein 90) and alters it function. HSP90 client protei Learn More

Hellebrin, Helleborus sp.
Product Number: H-1160

Product Name Price Qty
Hellebrin, Helleborus sp. - 1x1 mg
$45.00
Hellebrin, Helleborus sp. - 1x5 mg
$189.00
Cardiotonic glycoside. Potent inhibitor of Na+, K+ -ATPase (sodium pump) blocking the active efflux of Na+ and reuptake of K+ of this membra Learn More

Hypericin, Hypericum perforatum
Product Number: H-1042

Product Name Price Qty
Hypericin, Hypericum perforatum - 1x1 mg
$65.00
Hypericin, Hypericum perforatum - 1x5 mg
$255.00
Antiviral which also inhibits Protein Kinase C and to a lesser extent Casein Kinase II and MAP Kinase. Learn More

Ikarugamycin
Product Number: I-1192

Product Name Price Qty
Ikarugamycin - 1x500 μg
$185.00
Ikarugamycin - 1x1 mg
$310.00
Antiprotozoal antibiotic found to inhibit cholesteryl ester accumulation in macrophage. Inhibitor of clathrin-coated pits (CCP) dependent en Learn More

Ionomycin, Calcium Salt
Product Number: I-1015

Product Name Price Qty
Ionomycin, Calcium Salt - 1x1 mg
$70.00
Reportedly more effectivethan A23187 as a Ca++ionophore. Highly specific ionophore useful in studying Ca2+ transportation. Learn More

Ionomycin, Free Acid, Streptomyces conglobatus
Product Number: I-1014

Product Name Price Qty
Ionomycin, Free Acid, Streptomyces conglobatus - 1x1 mg
$70.00
Ionomycin, Free Acid, Streptomyces conglobatus - 1x5 mg
$265.00
Highly specific ionophore useful in studying Ca2+ transportation. Learn More

K-252a, Nocardiopsis sp.
Product Number: K-1006

Product Name Price Qty
K-252a, Nocardiopsis sp. - 1x100 μg
$95.00
A general protein kinase inhibitor. CaM (Ki=1.8 nM), PKA (Ki=25 nM), PKC (Ki=25 nM), PKG (Ki=20 nM), myosin light chain kinase (Ki=17 nM). Learn More

K-252b, Nocardiopsis sp.
Product Number: K-1008

Product Name Price Qty
K-252b, Nocardiopsis sp. - 1x100 μg
$95.00
A general protein kinase inhibitor. Learn More

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