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Product Description
Geldanamycin is a benzoquinone ansamycin antibiotic which binds to Hsp90 (Heat Shock Protein 90) and alters it function.
HSP90 client proteins play important roles in the regulation of the cell cycle, cell growth, cell survival, apoptosis, and oncogenesis.
Discounts for bulk available, inquire with our sales team.
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HSP90 client proteins play important roles in the regulation of the cell cycle, cell growth, cell survival, apoptosis, and oncogenesis.
Discounts for bulk available, inquire with our sales team.
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Seeking published scientists that has used our GELDANAMYCIN? Click on the HOT LINK for the free scientific paper.
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- http://iai.asm.org/content/69/9/5546.full.pdf+html br> br>
- http://www.jbc.org/content/283/19/13185.full.pdf+html br> br>
- http://mcr.aacrjournals.org/content/3/3/170.full.pdf+html br> br>
- http://cancerres.aacrjournals.org/content/67/16/7695.full.pdf+html br> br>
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Seeking published researchers utilizing our Geldanamycin product? Hit the hot link for the full paper.
br> br>1. Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans, Heather Senn, Rebecca S. Shapiro, et al, Jan 2012; 23: 268 - 283.
br> br>2. Unc45 Activates Hsp90-dependent Folding of the Myosin Motor Domain, Li Liu, Rajani Srikakulam, et al, May 2008; 283: 13185 - 13193.
br> br>3. Epidermal Growth Factor Receptors with Tyrosine Kinase Domain Mutations Exhibit Reduced Cbl Association, Poor Ubiquitylation, and Down-regulation but Are Efficiently Internalized, David Padrón, Mitsuo Sato, et al, Aug 2007; 67: 7695 - 7702.
br> br>4. Pim-1 Kinase Stability Is Regulated by Heat Shock Proteins and the Ubiquitin-Proteasome Pathway, Kate Petersen Shay, Zeping Wang, et al, Mar 2005; 3: 170 - 181.
br> br>5. Inhibition of HSP90 in Trypanosoma cruzi Induces a Stress Response but No Stage Differentiation, Sebastian E. B. Graefe, Martina Wiesgigl, et al, Dec 2002; 1: 936 - 943.
br> br>6. Role of the Heat Shock Protein 90 in Immune Response Stimulation by Bacterial DNA and Synthetic Oligonucleotides, Fu-Gang Zhu and David S. Pisetsky, Sep 2001; 69: 5546 - 5552.
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All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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