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Product Description
Puromycin is an aminoglsidic antibiotic. Puromycin is a protein inhibitor by inhibiting translation.
Puromycin's main function is used in cell biology as a selective antibiotic agent in cell culture systems.
Puromycin is an antibiotic used for selecting mammalian cell lines, which have been transformed by vectors that express puromycin-N-acetyl-transferase (PAC). It is toxic to procaryotic & eukaryotic cells.
Puromycin is derived from the Streptomyces alboniger bacterium.
Seeking published scientists that has used our PUROMYCIN? Click on the HOT LINK for the free scientific paper.
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- http://mcb.asm.org/content/27/17/6127.full.pdf+html br> br>
- http://jvi.asm.org/content/80/21/10325.full.pdf+html br> br>
- http://www.molbiolcell.org/content/19/8/3263.full.pdf+html br> br>
- http://cancerres.aacrjournals.org/content/66/1/151.full.pdf+html br> br>
- http://cancerres.aacrjournals.org/content/68/11/4277.full.pdf+html br> br>
- http://bloodjournal.hematologylibrary.org/content/111/1/328.full.pdf+html br> br>
- http://www.pnas.org/content/106/38/16275.full.pdf+html br> br>
- http://www.molbiolcell.org/content/15/6/2943.full.pdf+html br> br>
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Seeking published researchers utilizing our Puromycin.2HCL product? Hit the hot link for the full paper.
br> br>1. The Aryl Hydrocarbon Receptor Binds to E2F1 and Inhibits E2F1-induced Apoptosis, Jennifer L. Marlowe, Yunxia Fan, et al, Aug 2008; 19: 3263 - 3271.
br> br>2. Inhibition of Gastric Cancer Invasion and Metastasis by PLA2G2A, a Novel β-Catenin/TCF Target Gene, Kumaresan Ganesan, Tatiana Ivanova, et al,Jun 2008; 68: 4277 - 4286.
br> br>3. Ligand-Independent Regulation of Transforming Growth Factor ß1 Expression and Cell Cycle Progression by the Aryl Hydrocarbon Receptor, Xiaoqing Chang, Yunxia Fan, et al,Sep 2007; 27: 6127 - 6139.
br> br>4. Postentry Events Are Responsible for Restriction of Productive Varicella-Zoster Virus Infection in Chinese Hamster Ovary Cells, Renée L. Finnen, Kara R. Mizokami, et al, Nov 2006; 80: 10325 - 10334.
br> br>5. Physical and Functional Interaction between hMSH5 and c-Abl, Wei Yi, Tai-Hsien Lee, et al, Jan 2006; 66: 151 - 158.
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Additional Information
MSDS Documentation:COA Documentation: |
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| Product Number | P-1033 |
| CAS # | CAS [58-58-2] |
| Chemical Name | (S) 3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine,3'-(a-Amino-p-methoxy-hydocinnamamido)-3'-dexoy-N,N-dimethyladenosine.2HCl |
| Chemical Formula | C22H29N7O5.2HCl |
| Alternative Name | Puromycin | CAS [58-58-2]| Gene Selection Antibiotic| A.G. Scientific |
| Appearance | White to Off-White Powder |
| Merck Index | Merck Index: 13.8044.2001 |
| Molecular Weight | M.W. 544.43 |
| Purity | Purity: >98% |
| Solubility | Soluble in Water (50 mg/ml). |
| Storage Temp | -20ºC |
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