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Product Description
A potent and selective inhibitor of the TGF-β 1 receptor ALK5 (IC50 = 94 nM). It inhibits ALK4 only at higher concentrations (IC50 = 140 nM). Suppresses renewal in embryonic and induced pluripotent stem (iPS) cells and promotes their differentiation through its effect on Smad signaling pathway.
Additional Information
| Product Number | S-2122 |
| CAS # | 301836-41-9 |
| Chemical Name | 4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide |
| Chemical Formula | C22H18N4O3 |
| Appearance | Crystalline solid |
| Molecular Weight | 384.39 |
| Purity | >98% |
| Solubility | DMSO (20 mg/ml) or Ethanol (2 mg/ml) |
| Storage Temp | Store at -20°C. Protect from air and light |
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All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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