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Cytochalasin D- STRUCTURE-ANTI-FUNGAL-ACTIN FILAMENTS

CYTOCHALASIN D
Product Number: C-1070

        

Details

Cytochalasin D is a cell-permeable fungal toxin, 10-fold more effective than Cytochalasin B.Binds to barbed end of actin filaments, inhibiting the association and dissociation of subunits.Does not inhibit monosaccharide transport across cell membranes.Reported to exhibit antitumor activity, and induce apoptosis.

Additional Information

MSDS Documentation:
COA Documentation:
Package ID Refrigerated
CHEMACX X1009686-7
Chemical name (IUPAC) (7S,13E,16S,18R,19E,21R)-21-(ACETYLOXY)-7,18-DIHYDROXY-16,18-DIMETHYL-10-PHENYL[11]CYTOCHALASA-6(12),13,19-TRIENE-1,17-DIONE
Handling Protect from Light Store in Tightly Sealed Vial Warning.Toxic.
HAZARD CLASS Not Applicable
INCHI InChI=1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9+,15-14+/t17-,18+,22-,23-,24+,25-,26+,29+,30+/m0/s1
INDICATION Not Available
Soluble Soluble in Ethanol
MDL NUMBER MFCD00077706
Molecular Formula C30H37NO6
MP/BOILING POINT 255-260°C/712.1±60.0 °C at 760 mmHg
PACKING GROUP II
Peptide sequence Not Applicable
2013 Price 99
Size/Unit 1mg
SMILES C[C@H]1C/C=C/[C@H]2[C@@H](C(=C)[C@H]([C@@H]3[C@@]2([C@@H](/C=C/[C@@](C1=O)(C)O)OC(=O)C)C(=O)N[C@H]3Cc4ccccc4)C)O
THERAPEUTIC AREA Not Available
UN #'S UN 1544
USE Cytochalasin D is a member of the class of mycotoxins known as cytochalasins
Product Number C-1070
CAS # 22144-77-0
Chemical Formula C30H37NO6
Alternative Name Zygosporin A
Appearance White Solid
Handling Protect from Light Store in Tightly Sealed Vial Warning.Toxic.
Melting Point 255-260°C
Merck Index Merck Index: 12.2859.1996
Molecular Weight 507.63
Purity 97%
RTECS GZ4850000
Solubility CH2Cl2: Clear and colorless solution at 10 mg/ml
Storage Temp -20°C

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