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Product Description
Cell permeable triazolo-diamine compound; displays anti-proliferative properties in human cancer cells (IC50=20nM, 35nM and 92nM in HCT-116, HeLa, and A375 cells). Acts as a highly potent, ATP-competitive inhibitor of CDK1/cyclin B and CDK2/cyclin A (IC50=600pM and 500pM) with selectivity over VEGF-R2 and GSK-3β (IC50=32nM and 140nM).
Additional Information
COA Documentation: |
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| Product Number | C-1447 |
| Chemical Name | 5-Amino-3-((4-(aminosulfonyl)phenyl)amino)-N-(2,6-difluorophenyl)-1H-1,2,4-triazole-1-carbothioamide |
| Chemical Formula | C15H13F2N7O2S2 |
| Appearance | White to off-white solid. |
| Molecular Weight | M.W. 425.4 |
| Purity | Purity: ≥95% by HPLC |
| Solubility | Soluble in DMSO (10mg/ml). |
| Storage Temp | -20°C |
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All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
