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Proteasomes

Proteasomes are large protein complexes inside all eukaryotes and archaea, as well as in some bacteria. In eukaryotes, they are located in the nucleus and the cytomplasm. The main function of the proteasome is to degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Enzymes that carry out such reactions are called proteases. Proteasomes are part of a major mechanism by which cells regulate the concentration of particular proteins and degrade misfolded proteins.

A.G. Scientific delivers quality assured reagents directly to scientists, from small-scale to bulk orders. Our leadership in bulk supply allows us to provide custom product packaging and create multiple product forms. We offer “just in time” delivery, private labeling, and custom formulations for specific research needs.
 

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Antiserum to-NEDD8
Product Number: S-1090

Product Name Price Qty
Antiserum to-NEDD8 - 1x200 μl
$295.00
Source: Rabbit. Immunogen: Synthetic peptide corresponding to aa 20.32 of human NEDD8. Specificity: Recognizes human, mouse and rat NEDD8. D Learn More

Antiserum to-SUMO-1/Sentrin-1, Human
Product Number: S-1086

Product Name Price Qty
Antiserum to-SUMO-1/Sentrin-1, Human - 1x200 μl
$289.00
Source: Rabbit. Immunogen: Synthetic peptide corresponding to aa-1-21 of human SUMO-1/Sentrin-1. Specificity: Recognizes human, mouse, and r Learn More

Antiserum to-Ubc9, Human, Purified
Product Number: S-1092

Product Name Price Qty
Antiserum to-Ubc9, Human, Purified - 1x50 μg
$240.00
Source: Sheep purified. Liquid. Immunogen: Synthetic peptide corresponding to aa 147-158 of C-terminal human Ubc9. Specificity: Recognizes h Learn More

Calpain Inhibitor II
Product Number: C-1259

Product Name Price Qty
Calpain Inhibitor II - 1x5 mg
$70.00
Calpain Inhibitor II - 1x25 mg
$280.00
Inhibitor of calpain I, calpain II, cathepsin B and cathepsin L. Inhibits activation-induced programmed cell death. Also inhibits the peptid Learn More

clasto-Lactacystin β-lactone, Synthetic
Product Number: L-1055

Product Name Price Qty
clasto-Lactacystin β-lactone, Synthetic - 1x100 μg
$189.00
Synthetic. Highly specific, cell permeable, and irreversible 20S proteasome inhibitor. It is believed lactacystin acts as a precursor for cl Learn More

Epoxomicin, Synthetic
Product Number: E-1098

Product Name Price Qty
Epoxomicin, Synthetic - 1x50 ug
$130.00
Epoxomicin, Synthetic - 1x100 ug
$175.00
Cell permeable, potent, and selective proteasome inhibitor. More potent than Lactocystin. Inhibits the chymotrypsin-like, trypsin-like, and Learn More

Lactacystin
Product Number: L-1147

Product Name Price Qty
Lactacystin - 1x100 μg
$98.00
Lactacystin - 1x200 ug
$218.00
Lactacystin - 1x1 mg
$849.00
Cell permeable, irreversible proteasome inhibitor. Specifically inhibits the 20S and 26S proteasome. Blocks proteasome activity by targeting Learn More

Leupeptin, Hemisulfate
Product Number: L-1165

Product Name Price Qty
Leupeptin, Hemisulfate - 1x5 mg
$20.00
Leupeptin, Hemisulfate - 1x25 mg
$90.00
Leupeptin, Hemisulfate - 1x100 mg
$320.00
A reversible inhibitor of serine and cysteine proteases. Often used for inhibition of plasmin, trypsin, papain, kallikrein and cathepsin B. Learn More

MG-115
Product Number: M-1155

Product Name Price Qty
MG-115 - 1x1 mg
$45.00
MG-115 - 1x5 mg
$110.00
Potent, reversible proteasome inhibitor. Specifically inhibits the chymotrypsin-like activity of the proteasome. Learn More

MG-132
Product Number: M-1157

Product Name Price Qty
MG-132 - 1x1 mg
$15.00
MG-132 - 1x5 mg
$55.00
Potent, reversible and cell permeable proteasome inhibitor. Inhibits NF-κB activation. Learn More

MG-262 , Z-Leu-Leu-Leu-B(OH)2
Product Number: Z-1003

Product Name Price Qty
MG-262 , Z-Leu-Leu-Leu-B(OH)2 - 1x100 ug
$195.00
Highly potent and selective cell permeable inhibitor of the proteasome. Structurally similar to MG-132 (prod# M-1157) but has much higher po Learn More

Proteasome Inhibitor I (aldehyde)
Product Number: P-1149

Product Name Price Qty
Proteasome Inhibitor I (aldehyde) - 1x1 mg
$40.00
Proteasome Inhibitor I (aldehyde) - 1x5 mg
$115.00
Cell-permeable inhibitor of the multicatalytic proteinase complex (MPC, 20S proteasome) in HT4 cells. Causes accumulation of ubiquitinylated Learn More

Proteasome Inhibitor II (aldehyde)
Product Number: P-1151

Product Name Price Qty
Proteasome Inhibitor II (aldehyde) - 1x1 mg
$47.00
Proteasome Inhibitor II (aldehyde) - 1x5 mg
$150.00
Potent and cell-permeable proteasome inhibitor. Inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex ( Learn More

Proteasome Substrate I (Fluorogenic)
Product Number: P-1159

Product Name Price Qty
Proteasome Substrate I (Fluorogenic) - 1x1 mg
$30.00
Proteasome Substrate I (Fluorogenic) - 1x5 mg
$120.00
Fluorogenic proteasome substrate. Good for measuring the peptidase activity of the 20S proteasome Learn More

Proteasome Substrate II (Fluorogenic)
Product Number: P-1161

Product Name Price Qty
Proteasome Substrate II (Fluorogenic) - 1x5 mg
$130.00
Fluorogenic proteasome substrate. Good for measuring the peptidylglutamyl peptide-hydrolyzing activity of the 20S proteasome. Learn More

Proteasome Substrate III (Fluorogenic)
Product Number: P-1163

Product Name Price Qty
Proteasome Substrate III (Fluorogenic) - 1x5 mg
$71.00
Fluorogenic proteasome substrate. Also acts as a substrate for many other proteinases. Good for measuring the chymotrypsin-like peptidase ac Learn More

Proteasome Substrate IV (Fluorogenic)
Product Number: P-1165

Product Name Price Qty
Proteasome Substrate IV (Fluorogenic) - 1x1 mg
$37.00
Proteasome Substrate IV (Fluorogenic) - 1x5 mg
$143.00
Fluorogenic substrate for Alzheimer's disease amyloid A4-generating enzymes and for measuring the peptidase activity of the 20S proteasome. Learn More

Proteinase K
Product Number: P-1265

Product Name Price Qty
Proteinase K - 1x100 mg
$60.00
Proteinase K - 1x500 mg
$245.00
Proteinase K - 1x1 g
$475.00

Proteinase K is a non-specific serine protease used in the inactivation of Rnase and Dnases, Please ask about summer special pricing buy 1x100mg get 1x100mg free!

 

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Sirtinol
Product Number: S-1142

Product Name Price Qty
Sirtinol - 1x1 mg
$60.00
Sirtinol - 1x5 mg
$190.00
Specific cell-permeable inhibitor of the sirtuin family of NAD-dependent deacetylases with no effect on human HDAC1. Learn More

SUMO-1/Sentrin-1 (1-101), Human, Recombinant,
Product Number: S-1082

Product Name Price Qty
SUMO-1/Sentrin-1 (1-101), Human, Recombinant, - 1x250 μg
$190.00
Inactive precursor of SUMO-1/sentrin-1 produced in bacteria. Substrate for the characterization of SUMO-1/sentrin-1 specific proteases. Learn More

SUMO-1/Sentrin-1 (1-97), Human, Recombinant
Product Number: S-1084

Product Name Price Qty
SUMO-1/Sentrin-1 (1-97), Human, Recombinant - 1x500 μg
$290.00
Active standard for protein conjugation studies. Sufficient for about 40 assays. Recombinant human SUMO-1/Sentrin-1 (aa1-97) produced in bac Learn More

Ubiquitin Aldehyde, Synthetic
Product Number: U-1040

Product Name Price Qty
Ubiquitin Aldehyde, Synthetic - 1x50 μg
$133.00
Potent and highly specific inhibitor of all ubiquitin hydrolases. Blocks the hydrolysis of polyUbiquitin chains on substrate proteins by thi Learn More

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