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Product Description
GM6001, GM-6001 is a potent, cell-permeable, broad-spectrum hydroxamic acid inhibitor of matrix metalloproteinases (MMPs); (Ki = 400 pM for MMP-1; Ki = 500 pM for MMP-2; Ki = 27 nM for MMP-3; Ki = 100 pM for MMP-8; and Ki = 200 pM for MMP-9).
GM-6001 prevents the release of TNF-a in vivo and in vitro and abrogates endotoxin-induced lethality in mice.
GM-6001 prevents the release of TNF-a in vivo and in vitro and abrogates endotoxin-induced lethality in mice.
Additional Information
| Product Number | G-1231 |
| CAS # | CAS [142880-36-2] |
| Chemical Formula | C20H28N4O4 |
| Appearance | White to off-white solid |
| Molecular Weight | M.W. 388.5 |
| Purity | Purity: ≥95% |
| Solubility | DMSO, or 100% Ethanol |
| Storage Temp | -20°C |
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All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
