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Staurosporine, Cell permeable inhibitor of protein kinases

STAUROSPORINE, CELL PERMEABLE INHIBITOR OF PROTEIN KINASES
Product Number: S-1016

        

Details

A cell permeable general inhibitor of protein kinases. Inhibits CaM kinase ), myosin lightchain kinase , protein kinase A, protein kinase and protein kinase g .Inhibition of DNA Repair by a Herpes Simplex Virus Vector Enhances the Radiosensitivity of Human Glioblastoma Cells.

Additional Information

Alternate Name/Synonyms Staurosporine
COA Documentation:
Molecular Structure
CHEMACX X1000602-5
Chemical name (IUPAC) (5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14(5H)-ONE
Handling Warning.Toxic. May be Carcinogenic. Wear gloves/mask when handling product. Avoid contact by all means of exposure. Protect from Light
HAZARD CLASS Not Applicable
INCHI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1
INDICATION Glioma Brain Stem
Soluble Soluble in Ethyl Acetate and DMSO
MDL NUMBER MFCD18252446
Molecular Formula C28H26N4O3
MP/BOILING POINT 677.5±55.0 °C at 760 mmHg
PACKING GROUP Not Applicable
Peptide sequence Not Applicable
2013 Price 115
Size/Unit 1mg
SMILES C[C@@]12[C@@H]([C@@H](C[C@@H](O1)n3c4ccccc4c5c3c6n2c7ccccc7c6c8c5C(=O)NC8)NC)OC
THERAPEUTIC AREA Oncological Disorders
UN #'S Not Applicable
USE Potent inhibitor of phospholipid/calcium-dependent protein kinase. Inhibits the upregulation of VEGF expression in tumor cells
Product Number S-1016
CAS # 62996-74-1
Chemical Formula C28H26N4O3
Alternative Name Antibiotic AM-2282
Appearance Pale Yellow Solid
Handling Warning.Toxic. May be Carcinogenic. Wear gloves/mask when handling product. Avoid contact by all means of exposure. Protect from Light
Molecular Weight 466.5
Purity 98%
RTECS Not Applicable
Solubility Soluble in Ethyl Acetate and DMSO.
Storage Temp +4°C

Staurosporine, Cell permeable inhibitor of protein kinases

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  • Staurosporine | CAS 62996-74-1 | Cell Permeable Kinase inhibitor | A.G. Scientific