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FGF Signaling
Fibroblast growth factors, or FGFs, are a family of growth factors involved in angiogenesis, wound healing, and embryonic development. The FGFs are heparin-binding proteins and interactions with cell-surface-associated heparan sulfate proteoglycans have been shown to be essential for FGF signal transduction. FGFs are key players in the processes of proliferation and differentiation of wide variety of cells and tissues.
FREE REVIEW ARTICLES
- The role of FGF/Erk signaling in pluripotent cells, Fredrik Lanner and Janet Rossant. The role of FGF/Erk signaling in pluripotent cells. Development, 2010; 137: 3351 - 3360.
- Fibroblast Growth Factor (FGF) and FGF Receptor-Mediated Autocrine Signaling in Non-Small-Cell Lung Cancer Cells, Lindsay Marek, Kathryn E. Ware, et al. Fibroblast Growth Factor (FGF) and FGF Receptor-Mediated Autocrine Signaling in Non-Small-Cell Lung Cancer Cells. Mol. Pharmacol, 2009; 75: 196 - 207.
- FGF signaling acts upstream of the NOTCH and WNT signaling pathways to control segmentation clock oscillations in mouse somitogenesis, Matthias B. Wahl, Chuxia Deng, et al. FGF signaling acts upstream of the NOTCH and WNT signaling pathways to control segmentation clock oscillations in mouse somitogenesis. Development, 2007; 134: 4033 - 4041.
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