![Thapsigargin| CAS [ 67526-95-8 ] | Tumor promoting agent| Cell-permeable tumor promoter which promotes the discharge of Ca2+ from intracellular stores by specifically inhibiting endoplasmic reticulum Ca2+-ATPase, A.G. Scientific](http://www.agscientific.com/media/catalog/product/cache/1/thumbnail/56x/5e06319eda06f020e43594a9c230972d/T/-/T-1014_250x500_2.jpg "Thapsigargin| CAS [ 67526-95-8 ] | Tumor promoting agent| Cell-permeable tumor promoter which promotes the discharge of Ca2+ from intracellular stores by specifically inhibiting endoplasmic reticulum Ca2+-ATPase, A.G. Scientific")
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A23187, Free Acid - 1x10 mg$115.00
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Product Description
Cell-permeable tumor promoter which promotes the discharge of Ca2+ from intracellular stores by specifically inhibiting endoplasmic reticulum Ca2+-ATPase. This is achieved without the hydrolysis of inositolphopholipids.
Attached is a published reference from researchers who have used our Thapsigargin product.
- NEUROSCIENCE: Epac mediates PACAP-dependent long-term depression in the hippocampus, Jeanne Ster, Frédéric de Bock, et al., J. Physiol., Jan 2009; 587: 101 - 113.
- MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY: Prosurvival and Prodeath Effects of Hypoxia-inducible Factor-1Stabilization in a Murine Hippocampal Cell Line, Leila R. Aminova, Juan C. Chavez, et al., J. Biol. Chem., Feb 2005; 280: 3996 - 4003.
Additional Information
MSDS Documentation:COA Documentation: |
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| Product Number | T-1014 |
| CAS # | CAS [67526-95-8] |
| Chemical Formula | C34H50O12 |
| Appearance | Clear Colorless Film |
| Merck Index | Merck Index: 13.9342 |
| Molecular Weight | M.W. 650.8 |
| Purity | Purity: >98% |
| Solubility | Soluble in DMSO and Ethanol. |
| Storage Temp | -20°C |
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