Extracelluar domain of human TNF-R2 (aa1-257) is fused to the Fc portion of human IgG1. The recombinant fusion protein is produced in HEK 293T cells. rhTNF-R2:Fc can be used to detect membrane-bound TNF-α-mediated lysis, but requires concentrations >1000 ng/ml. Since TNF-R2:Fc preferentially interacts with the membrane-bound form of TNF-α. Crossreactivity: rhTNF-R2:Fc interacts with human TNF-α.