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Product Description
Vincristine.sulfate blocks mitotic spindle formation, which impedes the cell cycle in G2/M phase. Blocks binding of tubulin to microtubule proteins through depolymerization. Also acts as inducer to apoptosis; initiates Raf-1 activation & phosphorylation of Bcl-2 family proteins; and induction of p53 expression. Used as cancer chemotherapeutic agent. Plant alkaloid.
Additional Information
COA Documentation: |
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| Product Number | V-1055 |
| CAS # | CAS [2068-78-2] |
| Chemical Formula | C46H56N4O10.H2SO4 |
| Alternative Name | Leurocristine; VCR.sulfate |
| Appearance | White to Off White Solid |
| Merck Index | Merck Index: 13.10048.2001 |
| Molecular Weight | M.W. 923.1 |
| Purity | Purity: >98% |
| Solubility | Soluble in Methanol and Water. |
| Storage Temp | -20°C, Stock solutions <3 months at -20C |
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