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Product Description
A direct activator of soluble Guanylyl Cyclase (sGC), independent of Nitric Oxide.
Attached is a published reference from researchers who have used our YC-1 product. We respectfully thank them for their trust in our product.
- Ex vivo carbon monoxide delivery inhibits intimal hyperplasia in arterialized vein grafts, (2011), Atsunori Nakao, Chien-Sheng Huang, et al., Cardiovasc Res, 89: 457 - 463.
- RETINAL CELL BIOLOGY: Involvement of P2X7 Receptors in the Hypoxia-Induced Death of Rat Retinal Neurons, (2010), Tetsuya Sugiyama, Hidehiro Oku, et al., Invest. Ophthalmol. Vis. Sci., 51: 3236 - 3243.
- Pleiotropic Effects of YC-1 Selectively Inhibit Pathological Retinal Neovascularization and Promote Physiological Revascularization in a Mouse Model of Oxygen-Induced Retinopathy, (2010), M. DeNiro, A. Al-Halafi, et al., Mol. Pharmacol., 77: 348 - 367.
- RESEARCH ARTICLES: A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1, (2008), Shan Hua Li, Dong Hoon Shin, et al., Mol. Cancer Ther., 7: 3729 - 3738.
Additional Information
COA Documentation: |
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| Product Number | Y-1000 |
| CAS # | CAS[170632-47-0] |
| Chemical Name | 3-(5'-hydroxymethyl-2'furyl)-1-benzyl indazole |
| Chemical Formula | C19H16N2O2 |
| Appearance | Off-White to Yellow Solid |
| Molecular Weight | M.W. 304.4 |
| Purity | Purity: >98% |
| Solubility | Soluble in Chloroform, Methanol, and DMSO. |
| Storage Temp | +4°C |
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All products sold by A.G. Scientific are strictly for Laboratory, Preclinical Research, or Bioprocessing purposes only. They are not intended for Human Drug, Food Additive, Clinical or Household use.
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