Anthracyclines are anticancer compounds that were originally derived from Streptomyces and their anti-tumor activitieswere established in the 1960s. Anthracyclines are red aromatic polyketides and occur in variety of forms due to the structural differences in the aglycone and the different sugar residues attached.
Cefsulodin is a semi-synthetic third generation cephalosporin antibiotic with a structure similar to penicillins and beta-lactams. Cefsulodin is used by the water and dairy industries to test the quality of their products. AG Scientific continues to provide top quality testing reagents and supplies to water and dairy producers around the world. This article includes a … Continue reading Cefsulodin Sodium: FAQs, Protocols and Applications
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Beta Lactamase Mechanism Beta lactam antibiotics, like cephams and penicillin derivatives, have a four-member cyclic amide ring that inhibits the peptidoglycan layer synthesis in bacteria. A woven complex of sugar and protein pieces, these first-class bactericidal drugs destroy the integrity of the peptidoglycan layer. This method of bacterial cellular death is especially effective to Gram-positive bacteria … Continue reading The Ultimate Guide to Beta LactamaseRead More
The name 'antibiotic' was first given to the drugs that exhibit 'antibiosis' (meaning 'against life'), by Selman Waksman in 1942. After Vincenzo Tiberio discovered a mold (penicillium) in a well that displayed antibacterial, it led others to find the reasoning behind this. However, it was Alexander Fleming's (above) observations of fungus working against bacteria and concluded that it was due to the antibacterial compound, Penicillin.Read More
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