(1S,3R)-homo-ACPD

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(1S,3R)-homo-ACPD

A-1084
  • CAS: 111900-31-3
  • Formula: C8H13NO4
  • MW: 187.17
  • Appearance: White Powder
  • Purity: 97%

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(1S,3R)-homo-ACPD is the active isomer of trans-1,2-homo-ACPD. It is a selective metabotropic agonist. Systemic administration of (1S,3R)-homo-ACPD produced dose-dependent convulsions. Highly selective agonist for group ii mGluRs and has no effect on ionotropic excitatory amino acid receptors. (1S,3R)-homo-ACPD are the first agonist to show selectivity for mGlu receptors over iGlu receptors. (1S,3R)-homo-ACPD has been extensively used as a template to design mGlu receptor ligand. It is soluble in water.

Additional Information

Synonyms(1S,3R)-1-Amino-1-carboxycyclopentane-3-acetic acid
Product #A-1084
CAS #111900-31-3
Chemical Name(1S,3R)-1-Amino-1-carboxycyclopentane-3-acetic acid
FormulaC8H13NO4
MW187.17
AppearanceWhite Powder
Purity97%
SolubilitySoluble in Ethanol and Water
Storage Temp+4°C

Additional Information

MDL NumberMFCD00672624
InChIInChI=1S/C8H13NO4/c9-8(7(12)13)2-1-5(4-8)3-6(10)11/h5H,1-4,9H2,(H,10,11)(H,12,13)/t5-,8-/m0/s1
SMILESC1C[C@](C[C@@H]1CC(=O)O)(C(=O)O)N

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HandlingStore in Tightly Sealed Vial Protect from Light

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Certificate of Analysis 1A-1084, A7884.pdf
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