(+)-Aphidicolin Nigrospora oryzae

More Views

(+)-Aphidicolin Nigrospora oryzae

A-1026
  • CAS: 38966-21-1
  • Formula: C20H34O4
  • MW: 338.5
  • Appearance: Off-White Powder
  • Purity: >99%

0

0

0

0

Hazardous
Add to Cart Bulk Inquiry

Aphidicolin is a reversible Inhibitor of eukaryotic nuclear DNA replication. cell cycle at early S-phase.N K-independent Activation of c-Jun during Neuronal Apoptosis Induced by Multiple DNA-damaging Agents. DNA AND CHROMOSOMES: Cohesin Acetylation Promotes Sister Chromatid Cohesion Only in Association with the Replication Machinery. CELL BIOLOGY: RET Modulates Cell Adhesion via its Cleavage by Caspase in Sympathetic Neurons.

Low dose aphidicolin is an inhibitor of the DNA replicative polymerases α , δ, and ε1. Aphidicolin is a potent and specific inhibitor of B-family DNA polymerases2.

1.) http://www.jbc.org/content/290/48/28953.full.pdf+html

2.) http://nar.oxfordjournals.org/content/42/22/14013.full.pdf

Additional Information

SynonymsAPH
Product #A-1026
CAS #38966-21-1
Chemical Name(3-α,4-α,5-α,17-α)-3,17-Dihydroxy-4-methyl-9,15-cyclo-C,18-dinor-14,15-secoandrostane-4,17-dimethanol
FormulaC20H34O4
MW338.5
AppearanceOff-White Powder
Purity>99%
SolubilityMethanol: Clear colorless solution at 10 mg/ml
Melting Point230°C
Storage Temp+4°C. PROTECT FROM LIGHT! WARNING: TOXIC! POTENTIAL CARCINOGEN

Additional Information

Merck IndexMerck Index: 13.734.2001
MDL NumberMFCD00083214
ChemACXX1001937-7
InChIInChI=1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1
SMILESC[C@]12CC[C@H]([C@@]([C@@H]1CC[C@@H]3[C@@]24CC[C@@]([C@H](C3)C4)(CO)O)(C)CO)O

Additional Information

GHS Pictograms
RTECSPB9185000
HandlingWarning.Toxic. May be Carcinogenic. Wear gloves/mask when handling product. Avoid contact by all means of exposure.

Additional Information

Certificate of Analysis 1A-1026, J1034E.pdf
Certificate of Analysis 2A-1026, J1034D.pdf
Certificate of Analysis 3A-1026, J1034C.pdf
Close pop-up box

Personal Information

* Required Fields

Additional Information

No Items Found

Newsletter

Got Questions? We have Answers!

Our team of experts are standing by to help you in every possible way.

Real People, Real Time, Rapid Response

Chip Lindgren

Founder/CEO

Ken Smith

Operations

Kyle Anderson

Procurement & Business Development

Skyler King

Customer Service

 

Nicole Tran

Customer Service

 

Casey Kennedy

Marketing

 

 

 

 

 

BULK ENQUIRY FORM

* Required Fields

*
*
*
*
*
*Bulk OEM Multiple Catalog Custom Other
Prod#CAS#*PRODUCT NAMEGrade*Size*QtyTime Frame

Custom magento captcha module from Outsource Online