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TNFα & TNF receptor Superfamily
Tumor Necrosis Factor alpha (TNAα) is a group of cytokine produced by macrophages/monocytes and is responsible for a diverse range of signaling events within cells such as immunity, inflammation, differentiation, control of cell proliferation, necrosis and apoptosis. The protein is also important for resistance to infection and cancers. The TNF receptor superfamily includes FAS, CD40, CD27, and RANK. TNF family members exert their biological effects through the TNF receptor (TNFR) superfamily of cell surface receptors.
AG Scientific can ship FedEx directly to your lab, from small-scale to bulk orders. Our leadership in bulk supply allows us to provide custom product packaging and create multiple product forms. We offer “just in time” delivery, private labeling, and custom formulations for specific research needs.
FREE REVIEW ARTICLES
- Targeting TNF receptors in rheumatoid arthritis, Stephan Blüml, Clemens Scheinecker, et al. Targeting TNF receptors in rheumatoid arthritis. Int. Immunol, 2012; 24: 275 - 281.
- TNF receptor superfamily-induced cell death: redox-dependent execution, Han-Ming Shen and Shazib Pervaiz. TNF receptor superfamily-induced cell death: redox-dependent execution. FASEB J, 2006; 20: 1589 - 1598.