Antibiotic LL-Z1272γ; Ilicicolin D; NSC 287492
26166-39-2
404.9
C23H29ClO4
DMF, DMSO, Ethanol, Methanol
-20°C
Ascochlorin is an antitumor fungal metabolite which specifically inhibits matrix metalloproteinase-9 (MMP-9) activity through suppression of activator protein-1 (AP-1)-dependent induction of MMP-9 gene expression. Via AP-1 suppression, ascochlorin selectively kills MX-1 cells, a human breast cancer cell line lacking estrogen receptors.
Ascochlorin also shows activity against Newcastle disease and herpes simplex viruses.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
