Avermectin B1b

A-2661
  • CAS: 65195-56-4
  • Formula: C47H70O14
  • MW: 859.1
  • Appearance: White solid
  • Purity: >99% by HPLC

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*Please inquire the availability for this product. Avermectin B1b is the minor component (<20%) of a commercially available anthelmintic used to control parasitic nematodes in livestock. Avermectin B1b contains an isopropyl residue in the 25-position. In vitro and in vivo studies have shown this analogue to be active, but less potent than the B1a analogue

Additional Information

SynonymsC 076B1b
Product #A-2661
CAS #65195-56-4
FormulaC47H70O14
MW859.1
AppearanceWhite solid
Purity>99% by HPLC
SolubilitySoluble in water (partly), DMSO, ethanol, methanol, and DMF
Storage Temp-20°C
Therapeutic AreaInfectious Diseases
UseA macrocyclic lactone and anthelmintic agent

Additional Information

MDL NumberMFCD03701301
InChIInChI=1S/C47H70O14/c1-24(2)41-27(5)16-17-46(61-41)22-33-19-32(60-46)15-14-26(4)42(25(3)12-11-13-31-23-54-44-39(48)28(6)18-34(45(50)57-33)47(31,44)51)58-38-21-36(53-10)43(30(8)56-38)59-37-20-35(52-9)40(49)29(7)55-37/h11-14,16-18,24-25,27,29-30,32-44,48-49,51H,15,19-23H2,1-10H3/b12-11+,26-14+,31-13+/t25-,27-,29-,30-,32+,33-,34-,35-,36-,37-,38-,39+,40-,41+,42-,43-,44+,46+,47+/m0/s1
SMILESC[C@H]1/C=C/C=C/2\CO[C@H]3[C@@]2([C@@H](C=C([C@H]3O)C)C(=O)O[C@H]4C[C@@H](C/C=C(/[C@H]1O[C@H]5C[C@@H]([C@H]([C@@H](O5)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)OC)\C)O[C@]7(C4)C=C[C@@H]([C@H](O7)C(C)C)C)O

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