Bestatin (Ubenimix)

More Views

Bestatin (Ubenimix)

B-2547
  • CAS: 58970-76-6
  • Formula: C16H24N2O4
  • MW: 308.4
  • Appearance: White solid
  • Purity: >98% by HPLC

1

0

0

0

Hazardous
Add to Cart Bulk Inquiry

Bestatin is "pseudo"-dipeptide isolated from Streptomyces olivreticuli in 1976. Bestatin is a potent aminopeptidase B inhibitor with no carboxypeptidase activity. Bestatin acts as an immunomodulator by activating macrophages and T lymphocytes. Bestatin also exhibits antitumor activity and has been investigated in clinical trials. Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer1p>.

1.) Tsukamoto H, Shibata K, Kajiyama H, Terauchi M, Nawa A,Kikkawa F. 2008. Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer. BMC Cancer. 8:74.

 

Additional Information

SynonymsUbenimix, Inobestin, NK 421, Leukotriene A4 hydrolase, Aminopeptidase N
Product #B-2547
CAS #58970-76-6
FormulaC16H24N2O4
MW308.4
AppearanceWhite solid
Purity>98% by HPLC
SolubilitySoluble in water (<1 25), dmso (2 mg>
Melting Point233-236 °C
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseBestatin is a potent aminopeptidase inhibitor use in cancer

Additional Information

MDL NumberMFCD00083262
InChIInChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
SMILESCC(C)C[C@@H](C(=O)O)NC(=O)[C@H]([C@@H](Cc1ccccc1)N)O

Additional Information

Additional Information

Close pop-up box

Personal Information

* Required Fields

Additional Information

No Items Found

Newsletter

Got Questions? We have Answers!

Our team of experts are standing by to help you in every possible way.

Real People, Real Time, Rapid Response

Chip Lindgren

Founder/CEO

Ken Smith

Operations

Kyle Anderson

Procurement & Business Development

Skyler King

Customer Service

 

Nicole Tran

Customer Service

 

Casey Kennedy

Marketing

 

 

 

 

 

BULK ENQUIRY FORM

* Required Fields

*
*
*
*
*
*Bulk OEM Multiple Catalog Custom Other
Prod#CAS#*PRODUCT NAMEGrade*Size*QtyTime Frame

Custom magento captcha module from Outsource Online