Blasticidin S HCl Solution in HEPES buffer 10mg/ml

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Blasticidin S HCl Solution in HEPES buffer 10mg/ml

B-1247-SOL
  • CAS: 3513-03-9
  • Formula: C17H26N8O5.HCl
  • MW: 458.9
  • Appearance: Clear Solution
  • Purity: ≥98.0%

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*AG Scientific's Blasticidin S HCl solution is a sterile filterate solution.*

Blasticidin S.Hcl is an aminoacylnucleoside antibiotic isolated from Streptomyces griseochromogenes. It shows high efficacy against both eukaryotic and prokaryotic cells. Aside from its antimicrobial properties, blasticidin has displayed antiviral, antitumor, and antifungal properties and has been used as a selection agent. It has been used to select for cells containing the blsbsr, or BSD resistance gene as well as HEK293-T cells and HEK-D5 cells. Additionally, blasticidin is effective in preventing cell culture contamination and studying protein synthesis.

Blasticidin S.Hcl functions by inhibiting peptide bond formation at the ribosome. It blocks hydrolysis of peptidyl-tRNA due to the large ribosomal subunit's increased affinity for tRNA. Blasticidin S.Hcl's, longstanding application as a gene selection antibiotic, has a powerful new role in Genome editing utilizing the CRISPR/Cas9 system.

Concentration: 10 mg/ml in HEPES Buffer

 

Additional Information

Product #B-1247-SOL
CAS #3513-03-9
FormulaC17H26N8O5.HCl
MW458.9
AppearanceClear Solution
Purity≥98.0%
SolubilitySoluble in water. Clear and faint yellow solution (5mg/ml in water).
Storage TempStore at +4°C in a tightly sealed vial.

Additional Information

Merck Index14, 1316

Additional Information

Additional Information

msds 1B-1247-SOL, Blasticidin S HCl Solution, SDS, diamond format.pdf
Certificate of Analysis 1B-1247-SOL, J1105.pdf
Certificate of Analysis 2B-1247-SOL, H1188.pdf
Certificate of Analysis 3B-1247-SOL, H1183E.pdf
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