A cell-permeable compound that acts as a selective, potent , and reversible inhibitor of non-moscule myosin II. Inhibits the ATPase and gliding motility of human platelets (100M) whithout affecting myosin light chain kinase (MLCK)activity. Has been shown to block cell blebbing and to rapidly disrupt directed cell migration and cytokinesis in vertebrate cells. Does not disrupt mitosis or affect contractile ring assembly. New product, inquire for sizes pricing. Also refer to product B-1285 and B-1287
Additional Information
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Product # | B-1289 |
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CAS # | 674289-55-5 |
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Chemical Name | (+/-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE |
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Formula | C18H16N2O2 |
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MW | 292.3 |
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Appearance | Yellow Crystalline Solid |
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Purity | 98% |
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Solubility | Solube in DMSO, DMF. Sparing soluble in aqueous buffers. |
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Melting Point | 210-212 °C |
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Storage Temp | -20°C |
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Additional Information
| MDL Number | MFCD04113775 |
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| ChemACX | X1437461-9 |
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| InChI | InChI=1S/C18H16N2O2/c1-12-7-8-15-14(11-12)16(21)18(22)9-10-20(17(18)19-15)13-5-3-2-4-6-13/h2-8,11,22H,9-10H2,1H3 |
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| SMILES | Cc1ccc2c(c1)C(=O)C3(CCN(C3=N2)c4ccccc4)O |
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