Cefsulodin Sodium Salt

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Cefsulodin Sodium Salt C-1457
  • CAS: 52152-93-9
  • Formula: C22H19N4NaO8S2 Na
  • MW: 554.5
  • Appearance: White - yellowish crystalline powder.
  • Purity: ≥98.0%

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Cefsulodin Sodium Salt is a third generation cephalosporin antibiotic. Utilized in microbiology in CIN ( Cefsulodin-Irgasan-Novobiocin) Agar, it is used for the selective isolation of Yersinia enterocolitic. Also Cefsulodin chocolate blood agar is a selective medium for the recovery of Haemophilus influenzae from the respiratory secretions of patients with cystic fibrosis. CIN agar was first described by Schiemann as an alternative to MacConkey Agar and other commonly used media for isolation of Yersinia enterocolitica, a causative agent of gasteroenteritis. Cefsulodin has an important role in water testing where it is used as a contamination control inhibiting growth of unwanted bacteria other than E.Coli.

 Applications:

Clinical -

Used for the treatment of surgical infections caused by Pseudomonas aeruginosa.

Lab application -

  • Component of MI Agar used in water testing as a contamination control that inhibits the growth of bacteria other than E-Coli.
  • Used in Cefsulodin-Irgasan-Novobiocin Agar, a selsective media for the isolation of Yersinia enterocolitic.
  • Cefsulodin’s longstanding application identifying Yersinia enterocolitica has a powerful new role in Genome editing utilizing the CRISPR/Cas9 system.

 

Additional Information

SynonymsSulcephalosporin, Abbott 46811, CGP-7174/E, Cefomonil, Monaspor, Pseudomonil, Pseudocef, Pyocefal, Takesulin, Tilmapor, Ulfaret
Product #C-1457
CAS #52152-93-9
Chemical NameSODIUM (6R,7R)-3-[(4-CARBAMOYLPYRIDIN-1-IUM-1-YL)METHYL]-8-OXO-7-[[(2R)-2-PHENYL-2-SULFONATOACETYL]AMINO]-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLATE
FormulaC22H19N4NaO8S2 Na
MW554.5
AppearanceWhite - yellowish crystalline powder.
Purity≥98.0%
SolubilityFreely soluble in water & formamide. Slightly soluble in methanol; Very slightly soluble in ethanol.
Storage TempStore desiccated at -20°C.
Therapeutic AreaInfectious Diseases
UseCefsulodin sodium salt hydrate is a third generation β-lactam antibiotic and a member of the cephems subgroup of antibiotics.

Additional Information

MDL NumberMFCD07793338
ChemACXX1026792-4
InChIInChI=1S/C22H20N4O8S2.Na/c23-18(27)13-6-8-25(9-7-13)10-14-11-35-21-15(20(29)26(21)16(14)22(30)31)24-19(28)17(36(32,33)34)12-4-2-1-3-5-12;/h1-9,15,17,21H,10-11H2,(H4-,23,24,27,28,30,31,32,33,34);/q;+1/p-1/t15-,17-,21-;/m1./s1
SMILESc1ccc(cc1)[C@H](C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[n+]4ccc(cc4)C(=O)N)C(=O)[O-])S(=O)(=O)[O-].[Na+]

Additional Information

GHS Pictograms
RTECSUU1785000
HandlingKeep cool and dry. Protect from light and moisture. -20C recommended for long term, can store at +4°Cshort term.

Additional Information

msds 1C-1457, SDS.pdf
Certificate of Analysis 1C-1457, H1200.pdf
Certificate of Analysis 2C-1457, G1263M.pdf
Certificate of Analysis 3C-1457, G1263L.pdf

Additional Information

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